Objective: The approximate life span of a silicone maxillofacial prosthesis is as short as 1.5-2 years of clinical service, then a new prosthesis should be fabricated. The most common reason for re-making the prosthesis is silicone mechanical properties degradation. The aim of this study was to assess some mechanical properties of VST-30 silicone for maxillofacial prostheses after addition of intrinsic pigments.
Methods: Two types of intrinsic pigments (rayon flocking and burnt sienna); each of them was incorporated into silicone. One hundred and twenty samples were prepared and split into 4 groups according to the conducted tests (tear strength, hardness, surface roughness, and tensile strength and elongation percentage) with 30 samples for each test. Each group was equally split into three subgroups. Group (A) was without pigment (control group), group (B) was with rayon flocking and group (C) was with burnt sienna.
Results: Samples with rayon flocking showed a highly significant decrease in hardness and there was a significant increase in tear strength, while there were non-significant differences in surface roughness, tensile strength and elongation percentage. Samples with burnt sienna showed a highly significant increase in tear strength and a highly significant decrease in hardness, but surface roughness, tensile strength and elongation percentage showed non-significant differences. However, there were non-significant differences between experimental groups in all tests.
Conclusions: The addition of each of rayon flocking and burnt sienna changed the mechanical properties of the VST-30 silicone, while no superior pigment-silicone combination was revealed in all the conducted tests.
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http://dx.doi.org/10.1016/j.sdentj.2018.05.006 | DOI Listing |
Phys Chem Chem Phys
January 2025
State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Mechanoresponsive colloidal photonic crystals embedded in elastic solid matrices exhibit tunable optical properties under mechanical force, showing great potential for various applications. However, the response of colloidal crystals embedded in a liquid matrix remains largely unexplored. In this study, we investigate the structural and optical transitions of colloidal crystals composed of particles suspended in a liquid oligomer under pressing and shear forces.
View Article and Find Full Text PDFJ Mater Sci Mater Med
January 2025
Department of Nuclear Medicine, Chongqing University Cancer Hospital, No. 181 HanYu St, Shapingba District, Chongqing, 400030, PR China.
Human hair keratin, a natural protein derived from human hair, has emerged prominently in the field of wound repair, showcasing its unique regenerative capabilities and extensive application potential. However, it is a challenge for the keratin to efficiently therapy the impaired wound healing, such as combined radiation-wound injury. Here, we report a keratin/chitosan (KRT/CS) film for skin repair of chronic wounds in in rats with combined radiation-wound injury.
View Article and Find Full Text PDFJ Mol Model
January 2025
Department of Physics, University of Malakand, Chakdara, Dir (Lower), 18800, KP, Pakistan.
Context: The structural stability, ground state magnetic order, electronic, elastic and thermoelectric properties of NdMn in the C15, C14 and C36 polytypic phases is investigated. The magnetic phase optimization and magnetic susceptibility reveal that NdMn is antiferromagnetic (AFM) in C36 phase; and paramagnetic (PM) in C14 and C15 phases respectively. The band profiles and electrical resistivity show the metallic nature in all these polytypic phases and reveal that the C36 phase possesses smaller resistivity.
View Article and Find Full Text PDFJ Chem Inf Model
January 2025
Industrial and Molecular Pharmaceutics, Purdue University, West Lafayette, Indiana 47907, United States.
Drug-drug interaction can lead to diminished therapeutic effects or increased toxicity, posing significant risks, especially in polypharmacy, and cytochrome P450 plays an indispensable role in this interaction. Cytochrome P450, responsible for the metabolism and detoxification of most drugs, metabolizes about 90% of Food and Drug Administration-approved drugs, making early detection of potential drug-drug interactions. Over the years, in-silico modeling has become a valuable tool for predicting drug-drug interactions.
View Article and Find Full Text PDFACS Macro Lett
January 2025
Materials Science and Engineering Department, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
In complex networks and fluids such as the extracellular matrix, the mechanical properties are substantially affected by the movement of polymers both part of and entrapped in the network. As many cells are sensitive to the mechanical remodeling of their surroundings, it is important to appreciate how entrapped polymers may inhibit or facilitate remodeling in the network. Here, we explore a molecular-level understanding of network remodeling in a complex hydrogel environment through successive compressive loading and the role that noninteracting polymers may play in a dynamic network.
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