Structure-Based Classification and Anti-Cancer Effects of Plant Metabolites.

Int J Mol Sci

Collage of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Korea.

Published: September 2018

AI Article Synopsis

  • A variety of malignant cancers poses a significant health challenge globally, and traditional treatments often come with harmful side effects.
  • Plant metabolites are gaining attention as potential new sources for developing anti-cancer drugs due to their unique structures and activities against cancer.
  • The review outlines different plant metabolites and their effects on specific types of cancer, providing valuable insights for future drug development.

Article Abstract

A variety of malignant cancers affect the global human population. Although a wide variety of approaches to cancer treatment have been studied and used clinically (surgery, radiotherapy, chemotherapy, and immunotherapy), the toxic side effects of cancer therapies have a negative impact on patients and impede progress in conquering cancer. Plant metabolites are emerging as new leads for anti-cancer drug development. This review summarizes these plant metabolites with regard to their structures and the types of cancer against which they show activity, organized by the organ or tissues in which each cancer forms. This information will be helpful for understanding the current state of knowledge of the anti-cancer effects of various plant metabolites against major types of cancer for the further development of novel anti-cancer drugs.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163735PMC
http://dx.doi.org/10.3390/ijms19092651DOI Listing

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