Two new diphenyl ethers ( and ) and four new phenolic bisabolane sesquiterpenoids (⁻), together with five known related derivatives, were isolated from the culture of the endophytic fungus QQSG-3 obtained from a fresh branch of , which was collected from Huizhou city in the province of Guangdong, China. The structures of compounds ⁻ were determined by analyzing NMR and HRESIMS data. The absolute configurations of and were assigned by comparing their experimental ECD spectra with those reported for similar compounds in the literature. All isolates were evaluated for their α-glucosidase inhibitory activity, of which compounds , , , and showed strong inhibitory effects with IC values in the range of 1.5⁻4.5 μM.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165285PMC
http://dx.doi.org/10.3390/md16090307DOI Listing

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