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Shifting temporal trends and disparities in sarcoidosis mortality in the United States: A retrospective analysis from 1999 to 2020.
PLoS One
January 2025
Department of Internal Medicine, Seth GS Medical College and KEM Hospital, Mumbai, India.
Introduction: Sarcoidosis is an inflammatory disease characterized by granulomas, the etiology of which remains unclear. This study examines sarcoidosis-related mortality trends in the United States from 1999 to 2020, with a focus on disparities pertaining to patient sex, geographical location, and urbanization status.
Methods: We analyzed death certificate data from the CDC WONDER database, using ICD-10 code D86.
Generalized sarcoidosis associated with hypertrophic osteopathy in a Standardbred racehorse.
J Equine Vet Sci
January 2025
Department of Functional Sciences, Equine Division, Sports Medicine Section, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium. Electronic address:
Article Synopsis
- A Standardbred racehorse presented with exercise intolerance, weight loss, fever, and facial deformity, leading to diagnostic imaging revealing soft tissue swelling and periostitis.
- Radiological findings indicated bilateral periostitis in limbs, alongside skin lesions diagnosed as granulomatous dermatitis, suggesting equine sarcoidosis.
- The horse was euthanized after a rapid health decline, with post-mortem findings confirming generalized equine sarcoidosis and the detection of equine herpesvirus 5 DNA.
New phenotyping questionnaire for diagnosing sarcoidosis-associated small fiber neuropathy.
Brain Commun
August 2024
ILD Center of Excellence, Department of Pulmonology, St Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.
Small fiber neuropathy is a common complication in patients with sarcoidosis and its prevalence is estimated at 40-86%. The underlying mechanism influences the presentation of small fiber neuropathy. For example, patients with metabolic diseases are often associated with a classic length-dependent small fiber neuropathy pattern, while patients with inflammatory diseases are more often present with a non-length-dependent small fiber neuropathy.
View Article and Find Full Text PDFMethotrexate versus conventional disease-modifying antirheumatic drugs in the treatment of non-anterior sarcoidosis-associated uveitis.
Br J Ophthalmol
December 2024
Department of Internal Medicine and Clinical Immunology, Centre National de Références Maladies Autoimmunes et Systémiques Rares, Centre National de Références Maladies Autoinflammatoires Rares et Amylose Inflammatoire and INSERM, UMR S 959, Immunology- Immunopathology-Immunotherapy, Sorbonne Universités, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Aims: To compare the safety and efficacy of methotrexate (MTX), mycophenolate mofetil (MMF) and azathioprine (AZA) in non-anterior sarcoidosis-associated uveitis.
Methods: Retrospective study including non-anterior sarcoidosis-associated uveitis according to the revised International Workshop on Ocular Sarcoidosis criteria. The primary outcome was defined as the median time to relapse or occurrence of serious adverse events leading to treatment discontinuation.
Ocular Signs and Testing Most Compatible with Sarcoidosis-Associated Uveitis: A Latent Class Analysis.
Ophthalmol Sci
March 2024
Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California.
Purpose: This study aims to explore the potential subgroups of sarcoidosis-associated uveitis (SAU) within a multicenter cohort of uveitis participants.
Design: Cross-sectional study.
Participants: A cohort of 826 uveitis patients from a uveitis registry from 19 clinical centers in 12 countries between January 2011 and April 2015.
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