A 122Xe-122I generator system is described that produces 122I extraction efficiencies of approximately 60%. Radiocontaminants were less than 0.1% at the time of 122I removal following a 10 min ingrowth period. The chemical form of 122I was identified as [122I]iodide, and the [122I]iodide was remotely incorporated into radiopharmaceuticals for PET studies with an overall efficiency of as much as 40%.
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| http://dx.doi.org/10.1016/0883-2889(86)90183-8 | DOI Listing |
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A 122Xe-122I generator system is described that produces 122I extraction efficiencies of approximately 60%. Radiocontaminants were less than 0.1% at the time of 122I removal following a 10 min ingrowth period.
View Article and Find Full Text PDFThe positron emitter 122I (t1/2 3.6 min) was collected from a xenon-122/iodine-122 (122Xe/122I) generator and incorporated into an amphetamine analog, 2,4-dimethoxy-N,N-dimethyl-5-[122I]iodophenylisopropylamine (5-[122I]-2,4-DNNA). The remote synthesis was achieved in 3 min with a 50% radioincorporation yield and a product radiopurity of greater than 98%.
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