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Background: Endotoxin, a contaminant of cotton dust, is an experimental model for parkinsonism (PS).
Methods: We investigated associations between exposures to endotoxin, solvents, magnetic fields, and night shift work, and neurologist-determined PS among Shanghai women textile workers, including 537 retired cotton factory workers ages ≥50 years and an age-matched reference group of 286 retired textile workers not exposed to cotton dust. Repeat exams were conducted 2.5 years after enrollment among 467 cotton workers and 229 reference workers.
Results: We identified 39 prevalent PS cases and 784 non-cases. No consistent or statistically significant associations were observed for endotoxin, solvents, magnetic fields, or shift work with PS risk, severity, or progression.
Conclusions: Despite the null findings, additional studies of endotoxin exposure and risk of PS in other well-characterized occupational cohorts are warranted in view of toxicological evidence that endotoxin is a pathogenic agent and its widespread occurrence in multiple industries worldwide.
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http://dx.doi.org/10.1002/ajim.22906 | DOI Listing |
Medicine (Baltimore)
December 2024
Harran University Faculty of Medicine, Department of Cardiology, Şanliurfa, Turkey.
Development of industry in the modern world, the number of individuals working in noisy environments is increasing with each passing day. Noise causes an increase in the incidence of cardioembolic events, yet the relevant underlying pathophysiology remains unclear. In this study, we aimed to investigate the relationship between signal peptide and complement C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein-1 (SCUBE-1) in the pathophysiology of cardioembolic events in individuals exposed to noisy environments.
View Article and Find Full Text PDFAllergol Select
November 2024
Department of Dermatology and Allergy Biederstein, School of Medicine and Health, Technical University of Munich TUM).
Background: Anaphylaxis is a systemic allergic reaction that is potentially life-threatening. Occupational anaphylaxis is an anaphylaxis that occurs in an occupational context. In this position paper, we propose diagnostic criteria for occupational anaphylaxis and provide an overview of the current state of knowledge in terms of prevalence, triggers, prevention, and management.
View Article and Find Full Text PDFRSC Adv
December 2024
Beijing Key Laboratory of Clothing Materials R&D and Assessment, Beijing Engineering Research Center of Textile Nanofiber, Beijing Institute of Fashion Technology Beijing 100029 P. R. China
A sensitive compound was successfully obtained by coating polyaniline (PANI) on the surface of composite nanoparticles consisting of Au-loaded tin dioxide, named as PANI-Au-SnO, using an polymerization method. NH sensors in thin-film and fiber-shaped forms were prepared by inkjet printing and impregnation methods, respectively, based on PANI-Au-SnO. The response characteristics of these NH sensors developed from composite sensitive materials were investigated in detail.
View Article and Find Full Text PDFFront Public Health
December 2024
Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Background: Depression is becoming a significant burden and a potential cause of disability worldwide. According to a World Health Organization (WHO) study conducted in both developed and developing countries, the prevalence of depression is 10.4%.
View Article and Find Full Text PDFCurr Opin Allergy Clin Immunol
November 2024
Imperial College London National Heart and Lung Institute, London, UK.
Purpose Of Review: The textile manufacturing sector is a major contributor to the economies of several emergent economies in the global South. Respiratory disease, including byssinosis and chronic obstructive pulmonary disease (COPD), among textile workers appears to be common in this setting.
Recent Findings: Notably, little or no contemporary research has been published from countries, which are major global producers of textiles.
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