A low molecular weight substance which behaves like ouabain as inhibitor of brain membrane Na-K-ATPase and 3H-ouabain binding was found in plasma after saline expansion of extracellular fluid or angiotensin II infusion into the third brain ventricle in the rat. Intracerebroventricular infusion of angiotensin II antagonist, saralasin, blocks the increase of the Na-K-ATPase inhibitor produced by infusion of angiotensin II into the third ventricle or extracellular fluid saline expansion.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3109/10641968609044082 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!