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Qualitative comparison of decalcifiers for mouse bone cryosections for subsequent biophotonic analysis.
Sci Rep
January 2025
Leibniz Institute of Photonic Technology (Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research, LPI), 07745, Jena, Germany.
Bone tissue, with its complex structure, often necessitates decalcification of the hard tissue for ex vivo morphological studies. The choice of a suitable decalcification method plays a crucial role in preserving desired features and ensuring compatibility with diverse imaging techniques. The search for a universal decalcification method that is suitable for a range of biophotonic analyses remains an ongoing challenge.
View Article and Find Full Text PDFDevelopmental Toxicity of Disinfection Byproducts in F344 Rats: Effects on Pregnancy Maintenance and Eye Development.
Birth Defects Res
January 2025
Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee, USA.
Background: Epidemiological studies report associations of drinking water disinfection byproducts (DBPs) with adverse health outcomes, including birth defects. Here, we used a rat model susceptible to pregnancy loss (full-litter resorption; FLR) and eye malformations (anophthalmia, microphthalmia) to test 11 DBPs, including trihalomethanes, haloacetic acids (HAAs), and nitrogen-containing DBPs (N-DBPs).
Methods: Timed-pregnant F344 rats received gavage doses of chloroform, chlorodibromomethane, iodoform, chloroacetic acid, bromoacetic acid, dibromoacetic acid (DBA), diiodoacetic acid (DIA), trichloroacetic acid (TCA), dibromonitromethane, and iodoacetonitrile on gestation days (GD) 6-10.
Treatment of Xanthelasma Palpebrarum Using Trichloroacetic Acid 80.
J Clin Aesthet Dermatol
December 2024
All authors are affiliated with the Institute of Cosmetic and Laser Surgery in Oakville, Ontario. Canada.
Objective: We sought to analyze the effectiveness, recurrence, safety, and patient satisfaction rates following xanthelasma palpebrarum (XP) treatment with trichloroacetic acid (TCA) 80%.
Methods: This was a retrospective review of patients treated with TCA 80% for XP between January 2012 and August 2022. A prospective telephone questionnaire was administered to the same patient population to evaluate recurrence, patient satisfaction, and side effects.
Non-suppressed ion chromatography-tandem electrospray mass spectrometry using a short column for simultaneous analysis of dichloroacetic acid, trichloroacetic acid, and bromate: aqueous ammonia as the eluent additive.
Anal Methods
January 2025
State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing 210023, China.
Dichloroacetic acid (DCAA), trichloroacetic acid (TCAA), and bromate (BrO) are disinfection byproducts (DBPs) formed during drinking water treatment and pose health risks. Rapid and reliable detection of these DBPs is essential for ensuring water safety. Non-suppressed ion chromatography (IC)-electrospray ionization mass spectrometry (IC-ESI-MS/MS) offers a promising approach for simultaneous analysis of organic haloacetic acids (HAAs) and inorganic oxyhalides, but previous methods using toxic methylamine can pose health risks.
View Article and Find Full Text PDFRecurring Giant Conjunctival Cyst Effectively Treated With 20% Trichloroacetic Acid.
Cureus
November 2024
Department of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PRI.
Giant conjunctival cysts, though rare, can cause significant discomfort and functional impairment due to their size as well as their potential for rupture and recurrence. We report the case of a 51-year-old female who presented with a recurrent giant conjunctival cyst in her left eye, experiencing considerable discomfort and pain upon eye movement. The cyst, located in the left eye, had previously recurred after surgical excision, though visual acuity remained 20/20 bilaterally.
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