Interference of multiple photons via a linear-optical network has profound applications for quantum foundation, quantum metrology, and quantum computation. Particularly, a boson sampling experiment with a moderate number of photons becomes intractable even for the most powerful classical computers. Scaling up from small-scale experiments requires highly indistinguishable single photons, which may be prohibited for many physical systems. Here we report a time-resolved multiphoton interference experiment by using photons not overlapping in their frequency spectra from three atomic-ensemble quantum memories. Time-resolved measurement enables us to observe nonclassical multiphoton correlation landscapes, which agree well with theoretical calculations. Symmetries in the landscapes are identified to reflect symmetries of the optical network. Our experiment can be further extended to realize boson sampling with many photons and plenty of modes, which thus may provide a route towards quantum supremacy with nonidentical photons.
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http://dx.doi.org/10.1103/PhysRevLett.121.080501 | DOI Listing |
BMC Infect Dis
December 2024
Shenzhen Third People's Hospital, National Clinical Research Centre for Infectious Disease, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.
Background: Bacterial pathogens frequently encounter host-derived metabolites during their colonization and invasion processes, which can serve as nutrients, antimicrobial agents, or signaling molecules for the pathogens. The essential nutrient choline (Cho) is widely known to be utilized by a diverse range of bacteria and may undergo conversion into the disease-associated metabolite trimethylamine (TMA). However, the impact of choline metabolism on bacterial physiology and virulence remains largely unexplored.
View Article and Find Full Text PDFISA Trans
December 2024
State Key Laboratory of Tribology, Department of Mechanical Engineering, Tsinghua University, Beijing, PR China. Electronic address:
The conventional widely-used health monitoring methods for rotating machines have shortcomings such as the reliance on the selection of the preset parameters. Also, the strong noise interference caused by factors such as transmission path hinders the practical application of many fault feature extraction methods. To overcome these gaps, the digital twin notion is introduced and a new digital twin architecture called the Ramanujan Digital Twin (RDT) is designed.
View Article and Find Full Text PDFPoult Sci
December 2024
Yunnan Rural Revitalizing Education Institute, Yunnan Open University, Kunming 650101, Yunnan Province, PR China; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Guangxi Bufialo Research, Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, PR China; College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, Yunnan Province, PR China. Electronic address:
CD8 subunit alpha (CD8A) is an important gene in immunity and is involved in the functional regulation of T lymphocytes. However, the specific role and regulatory mechanism of CD8A in chicken T lymphocytes remain unknown. In this study, we overexpressed and interfered with CD8A in chicken T lymphocytes and found that interfering with CD8A expression inhibited the proliferation and induced the apoptosis of T lymphocytes and that the overexpression of CD8A promoted T lymphocyte activation.
View Article and Find Full Text PDFToxins (Basel)
December 2024
Division of Toxicology, Institute for Medical Research and Occupational Health, HR-10 000 Zagreb, Croatia.
The increasing use of products for medicinal, dietary, and recreational purposes has raised concerns about mycotoxin contamination in cannabis and hemp. Mycotoxins persist in these products' post-processing, posing health risks via multiple exposure routes. This study investigated cytotoxic and genotoxic interactions between cannabidiol (CBD) and the mycotoxin citrinin (CIT) using human cell models: SH-SY5Y, HepG2, HEK293, and peripheral blood lymphocytes.
View Article and Find Full Text PDFCurr Oncol
December 2024
Institute for Basic Sciences, Faculty of Physiotherapy, University of Physical Education, 31-571 Krakow, Poland.
Background: Multiple myeloma, a malignancy of plasma cells, often involves the disruption of vitamin D metabolism. Vitamin D, acting through its receptor (VDR), affects transcription factors like FOXO and sirtuins, which regulate cellular processes. The impact of physical activity on these markers in multiple myeloma patients is unclear.
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