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Electrochemotherapy: a good idea in recurrent basal cell carcinoma treatment. | LitMetric

Electrochemotherapy: a good idea in recurrent basal cell carcinoma treatment.

Melanoma Manag

Division of Oncologic Surgery, Melanoma & Sarcoma Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Published: February 2015

AI Article Synopsis

  • Basal cell carcinoma (BCC) is the most commonly diagnosed skin cancer in the Caucasian population, and surgical excision is the primary treatment method.
  • In cases where patients have surgical scars from multiple excisions or have undergone radiotherapy without clear margins, secondary surgery is not recommended.
  • A recent case study showed successful treatment of recurrent nasal BCC using electrochemotherapy (ECT) with intravenous bleomycin, resulting in complete lesion regression after 8 weeks and a disease-free interval of 7 months, highlighting ECT's role in improving quality of life for patients.

Article Abstract

Basal cell carcinoma (BCC) is the most common skin cancer in Caucasian population. Surgical excision is the gold standard treatment for BCC. Secondary surgical approach in patients presenting surgical scars after multiple surgical excisions or submitted to radiotherapy without obtaining a safe clearance margin, should be avoided. In recent years the use of electrochemotherapy (ECT) in head and neck cancers using intravenous bleomycin was specifically addressed and BCC resulted to be among tumors with the best response to ECT. We report a case of a recurrent nasal BCC treated with ECT with a complete regression of lesions after 8 weeks and a disease free period of 7 months. ECT is a good palliative treatment not affecting survival rate but improving quality of life in patients.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094671PMC
http://dx.doi.org/10.2217/mmt.14.28DOI Listing

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