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Landiolol: pharmacology and its use for rate control in atrial fibrillation in an emergency setting. | LitMetric

Landiolol: pharmacology and its use for rate control in atrial fibrillation in an emergency setting.

Eur Heart J Suppl

Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, Austria.

Published: January 2018

AI Article Synopsis

  • The article discusses landiolol, a newly approved ultra-short acting injectable beta-blocker in Europe, highlighting its pharmacokinetic and pharmacodynamic characteristics.
  • It presents initial experiences from studies involving Caucasian healthy volunteers and patients with atrial fibrillation.
  • In emergency situations, landiolol effectively reduces heart rate in tachycardic atrial fibrillation patients without causing significant drops in blood pressure, showing similar results in both Caucasian and Asian populations.

Article Abstract

This article provides new insight on landiolol, an ultra-short acting injectable betablocker, recently approved in Europe, with regard to its pharmacokinetic and pharmacodynamic profile, along with its first experience in Caucasian healthy volunteers and patients with atrial fibrillation. Landiolol as iv formulation exhibited in an emergency setting rapid rate reduction in patients with tachycardic atrial fibrillation without pronounced blood pressure drop both in caucasian and asian populations in similar manner.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909771PMC
http://dx.doi.org/10.1093/eurheartj/sux037DOI Listing

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