Vistriterpenoids A and B, Two New 24-Nor-oleanane Triterpenoids from Dodonaea viscosa.

Chem Biodivers

Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai, 201203, P. R. China.

Published: November 2018

AI Article Synopsis

  • Two new triterpenoids, vistriterpenoids A and B, were isolated from the plant Dodonaea viscosa, marking the first discovery of 24-nor-oleanane triterpenoids in this genus.
  • Their structures were determined through detailed spectroscopic analysis.
  • The newly identified compounds, along with two known ones, showed inhibitory effects against the enzyme PTP1B in laboratory tests.

Article Abstract

Two new triterpenoids, vistriterpenoids A (1) and B (2), and four known ones, were acquired from Dodonaea viscosa. Compounds 1 and 2 represent the 24-nor-oleanane triterpenoids isolated from the genus Dodonaea for the first time. Their structures were identified based on extensive spectroscopic methods. Compounds 1, 2, 5, and 6 exerted inhibitory activities against PTP1B in vitro.

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Source
http://dx.doi.org/10.1002/cbdv.201800426DOI Listing

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