Expression of type I and II interferon (IFN) was evaluated in gut-associated lymphoid tissue (GALT) and peripheral blood mononuclear cells (PBMCs) of HIV-1-positive patients on long-term, suppressive, antiretroviral therapy before and after probiotic supplementation. IFN subtypes and IFN were expressed at higher levels in GALT compared to PBMC, whereas an opposite trend of expression was recorded for IFN. An increase of IFN6, IFN10, IFN14, IFN17, and IFN21 and a decrease of IFN were observed in both anatomical sites after probiotic supplementation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109550 | PMC |
| http://dx.doi.org/10.1155/2018/1738676 | DOI Listing |
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