Healthcare-associated Legionnaires' disease often leads to fatal respiratory tract infection among hospitalized patients. In this report, three cases of Legionnaires' disease among patients in two different hospitals (Hospital A and Hospital B) were investigated. After conducting an epidemiologic and environmental investigation, the water distribution systems (WDSs) were identified as the possible source of infection, as serogroup 1 (1) was isolated from both clinical and environmental samples. Patients received aerosol therapy with nebulizers during their hospitalization. Based on the results of the investigation, the hospitals' infection control committees reviewed their policies for Legionnaires' disease prevention and implemented control measures focusing on using sterile fluids for aerosol treatments.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114232PMC
http://dx.doi.org/10.1155/2018/2570758DOI Listing

Publication Analysis

Top Keywords

legionnaires' disease
16
healthcare-associated legionnaires'
8
clusters healthcare-associated
4
legionnaires'
4
disease
4
disease hospitals
4
hospitals central
4
central greece
4
greece healthcare-associated
4
disease leads
4

Similar Publications

Legionella pneumophila, the causative agent of Legionnaires' disease, employs the Icm/Dot Type IV secretion system (T4SS) to replicate in amoebae and macrophages. The opportunistic pathogen responds to stress by forming 'viable but non-culturable' (VBNC) cells, which cannot be detected by standard cultivation-based techniques. In this study, we document that L.

View Article and Find Full Text PDF

Background: With various infectious disease risks to passenger ship travellers, guidance for infectious disease prevention, mitigation and management (PMM) exists. Emerging infections and emergencies necessitate updated, context-specific guidelines and practices. New evidence for infection PMM must be translated into guidance for governmental authorities and the passenger ship industry.

View Article and Find Full Text PDF

Background: species are the causative agent of Legionnaires' disease and, as ubiquitous waterborne bacteria, are prone to antimicrobial resistance gene (ARG) acquisition and dissemination due to the antimicrobial contamination of natural environments. Given the potential health risks associated with ARGs, it is crucial to assess their presence in the population.

Methods: The ARGs and were detected in 348 samples, isolates, and DNA extracts using conventional PCR.

View Article and Find Full Text PDF

Antibiotic susceptibility situation of environmental isolates in Southern Germany.

J Water Health

December 2024

Laboklin GmbH & Co KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.

Antimicrobial resistance is an emerging problem in hospitals and long-term healthcare facilities. Early detection of susceptibility pattern changes in pathogenic bacteria can prevent treatment failures. Therefore, this study chose to investigate the antibiotic susceptibility situation of isolates from hospitals and long-term healthcare facilities in Southern Germany.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!