We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies. Both, autoimmune limbic encephalitis and TEN are very rare diseases. The co-existence of the two diseases has not yet been reported. We speculate that the total of 18 drugs needed for the treatment of encephalitis might have increased the risk of TEN. Similar reports would be required to elucidate the pathophysiology of the co-existence.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120415 | PMC |
| http://dx.doi.org/10.1159/000491690 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Detection of anti-neuronal cell-surface antigen antibodies in pediatric patients with acute encephalitis in Japan.
Pediatr Int
January 2025
Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Japan.
The limbic and extra-limbic encephalitis associated with glutamic acid decarboxylase (GAD)-65 antibodies: an observational study.
Neurol Sci
December 2024
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, 510000, China.
We aimed to define the clinical features and outcomes of encephalitis associated with anti-GAD65 Abs. In addition, we reviewed cases published in the literature with GAD65 encephalitis. We retrospectively studied 482 consecutive patients attending a tertiary care center for evaluation of an autoimmune neurological disorder.
View Article and Find Full Text PDFAnti-Gamma Aminobutyric Acid B (GABA B) Antibody Receptor-Associated Autoimmune Encephalitis in Pregnancy: A Rare Condition.
Cureus
November 2024
Neurology, Park Hospital, Gurgaon, IND.
We report a primigravida 31-year-old female patient hospitalized at 32 gestational weeks with status epilepticus. In due course of illness, she developed refractory status epilepticus managed with induced coma with propofol and emergency early lower section caesarean surgery (LSCS). A battery of initial laboratory and radiological tests did not lead to a definite diagnosis.
View Article and Find Full Text PDFAcute Bilateral Vocal Cord Paralysis in a Patient With Anti-Leucine-Rich Glioma-Inactivated 1 (LGI1) Limbic Encephalitis.
Cureus
December 2024
Neurology, UT Health San Antonio, San Antonio, USA.
Autoimmune encephalitis is a disorder characterized by an autoantibody-mediated process that leads to brain inflammation. It is associated with neurological symptoms including cognitive issues, psychiatric problems, seizures, and autonomic dysfunctions. Anti-leucine-rich glioma-inactivated 1 limbic encephalitis (anti-LGI1 LE) is a rare type of autoimmune LE with a unique presentation, comprising neuropsychiatric disturbances, sleep disorders, and faciobrachial dystonic seizures (FBDS).
View Article and Find Full Text PDFAnti-Tr/DNER Antibody-associated Paraneoplastic Neurological Syndrome Presenting Limbic Encephalitis with Anaplastic Large Cell Lymphoma: A Case Report.
Intern Med
December 2024
Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan.
An 82-year-old man presented with acute progressive disturbance of consciousness. We suspected autoimmune limbic encephalitis because of abnormal magnetic resonance imaging findings in the bilateral temporal lobes and cerebrospinal fluid pleocytosis. The patient tested positive for anti-Tr/Delta/Notch-like epidermal growth factor-related receptor (DNER) antibodies, and a tissue biopsy revealed complications of anaplastic large cell lymphoma.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!