Typhoid fever with isolated left lateral rectus palsy.

BMJ Case Rep

Oxford University Clinical Research Unit, Patan Hospital, Lalitpur, Province - 3, Nepal.

Published: September 2018

A 17-year-old young woman presented to Patan Hospital, Kathmandu, Nepal, with high-grade fever and headache for 4 days and non-projectile vomiting for 1 day. She also had blurred vision with dizziness on and off. There was no abnormal physical finding. Enteric fever was suspected, and she was empirically started on azithromycin (20 mg/kg) for 7 days. She became afebrile after 2 days and was followed up in 7 days with diplopia since 5 days. At this time, the blood culture was positive for serovar typhi. On examination, there was isolated left lateral rectus palsy which accounted for her diplopia. Methylprednisolone (1 mg/kg) was prescribed which was tapered over 1 month and gradually her diplopia subsided. We hypothesise that vasculitic change in the blood vessel supplying the left abducens nerve could be causing the diplopia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129080PMC
http://dx.doi.org/10.1136/bcr-2018-225746DOI Listing

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