AI Article Synopsis

  • The study aimed to evaluate the effectiveness of adding platelet rich plasma (PRP) or Hyaluronic acid (HA) to fat graft myringoplasty (FGM) for repairing medium sized central tympanic membrane (TM) perforations.
  • A total of 69 patients were analyzed, with 21 receiving PRP, 23 receiving HA, and 25 undergoing pure FGM without any additives.
  • Results showed that both PRP (85.7% success) and HA (87% success) improved repair outcomes compared to pure FGM (60% success), indicating that using these materials enhances the closure of TM perforations.

Article Abstract

Objectives: To evaluate the effect of adding platelet rich plasma (PRP) or Hyaluronic acid (HA) to fat graft myringoplasty (FGM) for medium sized central tympanic membrane (TM) perforations.

Methods: This is a retrospective study conducted on 69 patients with medium sized central TM perforations. In 21 patients, PRP was used with the FGM; and in 23 patients, HA was used with the FGM; while in 25 patients, pure FGM was performed without adding an enhancing material.

Results: Successful TM perforation repair was achieved in 18 ears (85.7) with using PRP with FGM and in 20 ears (87%) with using HA with FGM and in 15 ears (60%) with pure FGM.

Conclusion: FGM with adding PRP or HA is more successful in closure of TM perforation than pure FGM in case of medium sized central TM perforation.

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Source
http://dx.doi.org/10.1016/j.amjoto.2018.08.004DOI Listing

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