AI Article Synopsis

  • - Calciphylaxis is a serious condition characterized by vascular calcifications and blood clots, leading to tissue necrosis, commonly seen in patients with end-stage renal disease (ESRD) but can also occur in other health issues.
  • - The condition has a high mortality rate primarily due to complications like sepsis and organ failure, making it particularly dangerous.
  • - A case study highlighted a patient with several health problems (ESRD, diabetes, hypertension, Mönckeberg's sclerosis) who faced diagnostic challenges because the necrotic lesions mimicked symptoms of systemic lupus erythematosus (SLE) with necrotizing vasculitis.

Article Abstract

Calciphylaxis is a condition with unclear etiopathogeny with vascular calcifications and thrombotic occlusion that lead to necrotic lesions. It is usually described in patients with end-stage renal disease (ESRD), but also in other conditions. The mortality rate is high, due to sepsis and internal organ failure. We present the case of a patient with multiple comorbidities (ESRD, diabetes, hypertension, Mönckeberg's sclerosis) with problems of differential diagnostic due to the necrotic lesions that mislead initially to systemic lupus erythematosus (SLE) with necrotizing vasculitis.

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