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Evaluating the pathological and clinical implications of errors made by an artificial intelligence colon biopsy screening tool.
BMJ Open Gastroenterol
January 2025
Histopathology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Objective: Artificial intelligence (AI) tools for histological diagnosis offer great potential to healthcare, yet failure to understand their clinical context is delaying adoption. IGUANA (Interpretable Gland-Graphs using a Neural Aggregator) is an AI algorithm that can effectively classify colonic biopsies into normal versus abnormal categories, designed to automatically report normal cases. We performed a retrospective pathological and clinical review of the errors made by IGUANA.
View Article and Find Full Text PDFColostomies for two lizards with cloacal prolapse.
J Vet Med Sci
January 2025
The Animal Disease Research and Support Association.
Two captive-bred lizards, a Western spiny-tailed iguana (Ctenosaura pectinata) and a bearded dragon (Pogona vitticeps), were evaluated for anorexia and absence of feces. The iguana had a recent cloacal prolapse, whereas the dragon had a repaired prolapse 20 days earlier. Exploratory celiotomy under anesthesia revealed a devitalized distal colon in the iguana and stenosis of ductal organs in the pelvic cavity in the dragon, leading to colostomies.
View Article and Find Full Text PDFReproductive Management of Reptiles.
Vet Clin North Am Exot Anim Pract
January 2025
Avian and Exotic Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Palackeho Trida 1946/1, Brno CZ 612 42, Czech Republic, EU. Electronic address:
Article Synopsis
- Research on reptile reproduction aims to create practical methods for clinical and lab settings, focusing on sex identification in species that look alike and artificial insemination for endangered reptiles.
- In pet reptiles, studies explore how hormones affect reproduction, particularly looking at ways to control hormonal levels.
- Gonadotropin-releasing hormone (GnRH) agonist implants can reduce reproductive hormones in female green iguanas but do not appear to affect male behavior or hormone levels, nor do they suppress reproduction in other lizard species like leopard geckos.*
Photobiomodulation therapy, also termed as low-level laser therapy, is commonly used as an adjunctive therapy for various medical conditions in veterinary practice. The ACTIVet PRO low-level laser has been used for treatment of various nondomestic species, yet the effects of dermal attributes such as pigment, feathers, or scales have not been evaluated. The effects of low-level laser therapy with the ACTIVet PRO have been investigated in laboratory animals, including a study in rats that evaluated the passage of laser light through the skin in postmortem samples.
View Article and Find Full Text PDFExploring the Influence of Neomorphic Gekkotan Paraphalanges on Limb Modularity and Integration.
J Exp Zool B Mol Dev Evol
January 2025
Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.
Digital specializations of geckos are widely associated with their climbing abilities. A recurring feature that has independently emerged within the sister families Gekkonidae and Phyllodactylidae is the presence of neomorphic paraphalanges (PPEs), usually paired, paraxial skeletal structures lying adjacent to interphalangeal and metapodial-phalangeal joints. The incorporation of PPEs into gekkotan autopodia has the potential to modify the modularity and integration of the ancestral limb pattern by affecting information flow among skeletal limb parts.
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