Glucosamino nucleic acids (GANAs) bearing a β-N-glycoside bond between carbon 1 of the glucosamine and the nucleobase nitrogen were synthesized and incorporated into oligonucleotides (4',6'-GANA and 3',6'-GANA). The thermal stability of oligonucleotide duplexes containing the GANA zwitterionic nucleotides was also investigated.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2018.08.024 | DOI Listing |
Publication Analysis
Top Keywords
glucosamino nucleic
8
nucleic acids
8
synthesis cationic
4
cationic glucosamino
4
acids stabilizing
4
stabilizing oligonucleotides
4
oligonucleotides glucosamino
4
acids ganas
4
ganas bearing
4
bearing β-n-glycoside
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!