In our experiment, we deal with the phenomenon of radiation hormesis and improvements based on this phenomenon to different growing characteristics of the fast-growing, very feed-efficient, and with a high-yielding carcass hybrid of the Peking duck (Cherry Valley SM3 medium). In the first phase of the project, we exposed hatching duck eggs to low and middle doses of gamma radiation 60Co (0.06-2.00 Gy) before placing them into a setter in the hatchery. We then followed the standards of artificial incubation. The treatment of our chosen doses of gamma radiation has no significant influence on the history and results of hatching (from 85.5% to 92.6%); it was influenced only by the basic management and husbandry of the parent stock. From our observations we confirm that the Peking duck, despite genetic progress, retained its vitality and robustness. Its embryos are not damaged even with a dose of 2 Gy, which is over the deterministic effect of ionizing radiation for vertebrates. At the end of the fatting period a significant drop in plasma phosphorus levels was measured in the ducks; however, it was dependent on the radiation dose to which the hatching eggs were exposed (r = -0.965). A positive effect of radiation hormesis may be expected in the case of 1 Gy dose where the highest values of mean corpuscular hemoglobin, mean corpuscular hemoglobin, combined hemoglobin, and drake weight were measured. Lower and higher doses of ionizing radiation used did not display these effects.
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http://dx.doi.org/10.3382/ps/pey391 | DOI Listing |
Dokl Biochem Biophys
January 2025
State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 123098, Moscow, Russia.
Background: The effects of ionizing radiation (IR) involve a highly orchestrated series of events in cells, including DNA damage and repair, cell death, and changes in the level of proliferation associated with the stage of the cell cycle. A large number of existing studies in literature have examined the activity of genes and their regulators in mammalian cells in response to high doses of ionizing radiation. Although there are many studies, the research in effect of low doses of ionizing radiation remains limited.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Regenerative Medicine, National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 249036 Obninsk, Russia.
The evolution of man on Earth took place under conditions of constant exposure to background ionizing radiation (IR). From this point of view, it would be reasonable to hypothesize the existence of adaptive mechanisms that enable the human organism to safely interact with IR at levels approximating long-term natural background levels. In some situations, the successful operation of molecular mechanisms of protection against IR is observed at values significantly exceeding the natural background level, for example, in cancer cells.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun, Jilin 130021, PR China. Electronic address:
Exposure of PM2.5 can cause different degrees of lung injury, which is referred with inflammatory response. Some evidences showed that low-dose radiation (LDR) induces hormesis in immune, however, it is unknown if LDR ameliorates the PM2.
View Article and Find Full Text PDFInt J Radiat Biol
January 2025
Department of Radiation Biosciences, Radiation Effects Research Foundation, Hiroshima, Japan.
Purpose: Radiation exposures do not seem to increase the proportion of mice dying from tumors, but rather cause a shift in the appearance of spontaneous cancers, allowing them to appear earlier, and hence produce a life shortening effect. Then, it was possible to estimate the effect of the dose rate on the carcinogenic effects of radiation using life shortening effects as a measure.
Conclusion: The dose response for the induction of life shortening was linear under acute exposure conditions, which indicates that the response under chronic exposure conditions is also likely to be linear, and hence the dose rate factor (DRF) would be constant throughout the dose.
Pain Rep
February 2025
Department of Physical Medicine & Rehabilitation, College of Medicine, University of Florida, Gainesville, FL, USA.
Introduction: Factors contributing to individual differences in knee osteoarthritis remain elusive. Dispositional traits and socioeconomic status are independent predictors of mental and physical health, although significant variability remains. Dispositional traits serve as the biological interface for life experiences.
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