Three Skulls Dating from the French Revolutionary Years Diagnosed with Tinea Capitis: A Paleopathologic Approach.

J Craniofac Surg

Assistance Publique - Hôpitaux de Paris, Necker - Enfants Malades University Hospital, Department of Maxillofacial and Plastic Surgery, Paris Descartes University, Sorbonne Paris Cité University, Paris, France.

Published: October 2018

The Musée Dupuytren was a Parisian pathology museum established in 1835. This museum hosted 3 skulls with severe craniofacial lesions initially tagged as aggressive forms of tinea capitis. The aim of this study was to investigate these specimens and discuss the initial diagnosis. Historical investigations were conducted based on the biographic data from the tags of the 3 skulls and entries on the catalog of the museum. Age was determined using dentition and the patency of cranial base synchondroses. The computed tomography scans were performed using standard medical devices. The 3 skulls were from the late 18th to early 19th century. Skull № 1 was a 5-year-old child and presented with microcephaly and extensive vault osteolysis compatible with an aggressive benign lesion, a malignant tumor, or a chronic infection. Skull № 2 was a 12- to 18-year-old teenager and presented with symmetrical porotic hyperostosis compatible with undernutrition and various hematologic conditions causing prolonged anemia, but also with chronic inflammation and/or infection. Skull № 3 was also from a 12- to 18-year-old teenager and presented with focal temporal osteolysis compatible with an aggressive benign or a low-grade malignant temporal soft-tissue lesion or with chronic infection. These skulls contribute to the understanding of the concept of tinea in the 19th century. They are furthermore windows on the sanitary and social conditions in Paris in the years following the French revolution and during the Napoleonian wars.

Download full-text PDF

Source
http://dx.doi.org/10.1097/SCS.0000000000004728DOI Listing

Publication Analysis

Top Keywords

skull №
12
tinea capitis
8
19th century
8
osteolysis compatible
8
compatible aggressive
8
aggressive benign
8
chronic infection
8
infection skull
8
№ 12-
8
12- 18-year-old
8

Similar Publications

Cranioencephalic functional lymphoid units in glioblastoma.

Nat Med

October 2024

German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, a partnership between DKFZ and University Hospital Essen, University Duisburg-Essen, Essen, Germany.

The ecosystem of brain tumors is considered immunosuppressed, but our current knowledge may be incomplete. Here we analyzed clinical cell and tissue specimens derived from patients presenting with glioblastoma or nonmalignant intracranial disease to report that the cranial bone (CB) marrow, in juxtaposition to treatment-naive glioblastoma tumors, harbors active lymphoid populations at the time of initial diagnosis. Clinical and anatomical imaging, single-cell molecular and immune cell profiling and quantification of tumor reactivity identified CD8 T cell clonotypes in the CB that were also found in the tumor.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates if a PSMA-PET scan from the skull base to proximal thigh is sufficient for detecting bone metastases in prostate cancer patients.
  • A retrospective analysis of 1050 PET scans revealed significant correlations between PSA levels and the presence of bone metastases, identifying that most metastases occur in patients with higher numbers of total metastases.
  • The study concludes that specific PSA cut-off values (11.15 ng/mL for below the thigh and 12.86 ng/mL for above the skull base) can effectively indicate the presence of bone metastases, showcasing the potential for optimized imaging strategies.
View Article and Find Full Text PDF

Natural history of mild trigonocephalic deformities.

J Neurosurg Pediatr

October 2023

2Division of Neurosurgery, Connecticut Children's, Hartford, Connecticut; and.

Objective: Ridging along the metopic suture line can be a common cause of concern for parents and has been theorized to represent a mild form of trigonocephaly, a cranial deformity associated with risks of negative cosmetic outcomes, if not surgically corrected. Yet the literature contains sparse reports of long-term cosmetic results or expectations for infants with isolated metopic ridging compared with those with severe trigonocephaly, or even what objective metrics discriminate isolated metopic ridging from severe trigonocephaly. Therefore, the authors' goals for this study were to 1) quantify the degree of frontal deformity among patients with metopic ridge, metopic craniosynostosis, and normocephalic head shapes; and 2) document the natural history of frontal deformities in isolated metopic ridge patients in the 1st year of life.

View Article and Find Full Text PDF

Skull-Base Chordoma Mimicking Optic Neuritis.

J Neuroophthalmol

December 2023

Al-Bahar Ophthalmology Center (AAA, RSB), Ibn Sina Hospital, Kuwait City, Kuwait; and Department of Radiology (FD), Ibn Sina Hospital, Kuwait City, Kuwait .

View Article and Find Full Text PDF

Purpose: The goal of this study is to investigate treatment planning of total marrow irradiation (TMI) using intensity-modulated spot-scanning proton therapy (IMPT). The dosimetric parameters of the intensity-modulated proton plans were evaluated and compared with the corresponding TMI plans generated with volumetric modulated arc therapy (VMAT) using photon beams.

Methods: Intensity-modulated proton plans for TMI were created using the Monte Carlo dose-calculation algorithm in the Raystation 11A treatment planning system with spot-scanning proton beams from the MEVION S250i Hyperscan system.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!