AI Article Synopsis
- Urine is the most commonly used biological sample for drug testing, but some individuals attempt to submit animal urine to avoid detection.
- The study aimed to differentiate between human and various animal urine samples using quantitative 1H-NMR spectroscopy and to identify specific biomarkers for this distinction.
- Results showed distinct metabolite profiles between human and animal urine, revealing several key metabolites that can be used for discrimination.
Article Abstract
Urine was most commonly used biological sample in drug test. To create a false-negative test result, some drug abusers were reported to submit animal urine instead of their own. So, the purpose of this study was to compare and differentiate human from animal urine (Rat 370, Pig 12, Horse 10, Cat 8, Dog 13, Cow 10, Monkey 10) samples through the uses of quantitative 1H-NMR and to find biomarkers that can be used for the discrimination of human urine from animal urine. The 1H-NMR spectroscopy was employed and metabolomic analysis with multivariate statistics was carried out. Human urine samples and animal urine samples showed different patterns in metabolites profile and several characteristic metabolites were identified.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/jat/bky061 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!