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An Exploration of the Interplay Between Caffeine and Antidepressants Through the Lens of Pharmacokinetics and Pharmacodynamics.
Eur J Drug Metab Pharmacokinet
January 2025
Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW, 2007, Australia.
Caffeine consumption is regarded as a widespread phenomenon, and its usage has continued to increase. In addition, the growing usage of antidepressants worldwide and increase in mental health disorders were shown in recent statistical analyses conducted by the World Health Organisation. The coadministration of caffeine and antidepressants remains a concern due to potential interactions that can alter a patient's response to therapy.
View Article and Find Full Text PDFRelationship between antihistamine residues in wastewater and airborne pollen concentrations: Insights into population-scale pollinosis response.
Sci Total Environ
January 2025
Swiss Federal Institute of Aquatic Science and Technology, Eawag, Dübendorf, Switzerland.
Pollinosis is the most prevalent allergic disorder. Assessing the impact of real-world pollen exposure on symptoms remains challenging due to extensive patient-level efforts required. This study explores the potential of wastewater-based epidemiology (WBE) to investigate the relationship between airborne pollen concentrations and antihistamine residues in wastewater as an indicator of pollinosis symptom treatment at the population-scale.
View Article and Find Full Text PDFA Review on Medicinal Approaches of Novel Imatinib Derivatives.
Curr Top Med Chem
January 2025
Department of Pharmacy, Panipat Institute of Engineering & Technology (PIET) Samalkha, Panipat, Haryana-132102, India.
Phenyl amino pyrimidine attracts researchers due to its versatile scaffold and medicinal significance. This significant moiety present in the Imatinib contributed to medicinal chemistry. In this manuscript, we reviewed various derivatives of Imatinib containing 2-phenylaminopyrimidine, which has a variety of roles, especially in the anti-cancer category.
View Article and Find Full Text PDFRelative Survival, Conditional Survival, and Causes of Death in Patients with Early Gastric Cancer, with a Focus on Differences Between Cardia and Non-Cardia Cancer.
Cancers (Basel)
December 2024
Section of Gastroenterology and Hepatology, Margaret M. and Albert B. Alkek Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
: Many researchers believe that cardia (CGC) and non-cardia (NCGC) are two different types of tumors, having different features like incidence rate, risk factors, geographical location, and socioeconomic status. This study aims to investigate the causes of death (COD) survival rates among early gastric cancer patients with a focus on differences between CGC and NCGC. : This retrospective study employed SEER*stat software (version 8.
View Article and Find Full Text PDFInvited review: Udder cleft dermatitis in dairy cows.
J Dairy Sci
January 2025
Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium.
Udder cleft dermatitis (UCD) is a common dermatological condition of the udder skin in dairy cows. It is generally considered to be a multifactorial disease, being described in a rather limited amount of literature. Its cow and within-herd prevalence widely ranges between studies depending on the study characteristics, environment and breed.
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