A quinoxalinone-bohemamine hybrid compound quinohemanine (1), together with 1-methyl-2(H)-quinoxalin-2-one (2), was isolated from Streptomyces sp. CPCC 200497, a producer of quinomycins and bohemamines. Compounds 1 and 2 were purified using standard chromatographic methods, and their structures were defined through interpretation of HRMS, 1D, and 2D NMR data. Both 1 and 2 displayed moderate cytotoxicity against cancer cell line HepG2.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41429-018-0084-5 | DOI Listing |
Publication Analysis
Top Keywords
quinoxalinone-bohemamine hybrid
8
hybrid compound
8
streptomyces cpcc
8
cpcc 200497
8
quinohemanine quinoxalinone-bohemamine
4
compound streptomyces
4
200497 quinoxalinone-bohemamine
4
compound quinohemanine
4
quinohemanine 1-methyl-2h-quinoxalin-2-one
4
1-methyl-2h-quinoxalin-2-one isolated
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!