Objective: We have previously described the central nature of simple cases for financial feasibility of proton beam therapy centers-especially four- to five-room centers. In the 5 years since that publication, such construction has slowed drastically, and smaller, single-room projects are in vogue. We now seek to show under what circumstances a single-room system is optimally financially viable.
Materials And Methods: A "standard" construction cost and debt for a single gantry system of $40 million was presumed, with 75% of the construction funded through standard 20-year financing. We then modeled a statistical analysis, deriving the optimal case mix required daily to cover construction and debt service costs.
Results: We previously published that a single gantry treating only complex patients would need to apply 85% of its treatment slots simply to service debt, though it would cover its debt treating 4 hours of simple patients. As the business model has changed, debt maintenance, profit and operational costs have somewhat reduced the business case for adding a large number of simple patients. Debt maintenance is possible with as little as 13% of daily patients for a 40% Medicare case mix, but these numbers are critically sensitive to continued patient throughput.
Conclusions: Even in a single-room system, reducing overall debt, using tax-exempt financing, and having a case load emphasizing simple, private payer patients is paramount to fiscal health of the facility. Unused capacity is a huge risk if insufficient patients are available.
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http://dx.doi.org/10.1016/j.jacr.2018.07.020 | DOI Listing |
Phys Med Biol
January 2025
Department of Radiation Oncology, The University of Kansas Medical Center, Department of Radiation Oncology, University of Kansas Medical Center, USA, Kansas City, Kansas, 66160-8500, UNITED STATES.
Proton minibeam radiation therapy (pMBRT) dose profile is characterized by highly heterogeneous dose in the plane perpendicular to the beam direction and rapidly changing depth dose profiles. Typically, dose measurements are benchmarked against in-house Monte Carlo simulation tools. It is essential to have a treatment planning system (TPS) that can accurately predict pMBRT doses in tissue and be available via commercial platform for preclinical and clinical use.
View Article and Find Full Text PDFSoc Sci Med
January 2025
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Background: Gay, bisexual, and other men who have sex with men (GBMSM) are disproportionately affected by housing insecurity across the US. This study examined the association between homelessness and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among GBMSM in the United States and investigated the modifying effect of injection drug use.
Methods: 47,750 cisgender GBMSM who participated in the American Men's Internet Survey from 2017 to 2021 and who self-reported not living with HIV were included in this secondary, cross-sectional analysis.
Front Oncol
November 2024
P-Cure Ltd./Inc, Shilat, Israel.
Purpose: The focus of this article is to describe the configuration, testing, and commissioning of a novel gantry-less synchrotron-based proton therapy (PT) facility.
Materials And Methods: The described PT system delivers protons with a water equivalent range between 4 and 38 cm in 1800 energy layers. The fixed beam delivery permits a maximum field size of 28 × 30 cm.
BMC Public Health
August 2024
Department of Pediatrics, Faculty of Medicine, University of British Columbia, BC Children's Hospital, Rm 2D19, 4480 Oak Street, Vancouver, BC, V6H 3V4, Canada.
Background: Burn injuries are a significant public health concern, closely linked to housing conditions and socioeconomic status. Residents in socioeconomically deprived neighbourhoods are at increased risk of exposure to hazards due to older and poorer housing conditions and limited access to fire protection measures. Individual behaviours such as substance use, smoking, and hoarding are often highlighted as primary causes of residential fires, overshadowing the broader socioeconomic and structural factors that also play a significant role in housing safety.
View Article and Find Full Text PDFMed Phys
June 2024
Department of Radiation Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Background: Minibeam represents a preclinical spatially fractionated radiotherapy modality with great translational potential. The advantage lies in its high therapeutic index (compared to GRID and LATTICE) and ability to treat at greater depth (compared to microbeam). Proton minibeam radiotherapy (pMBRT) is a synergy of proton and minibeam.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!