Only two international organisations have a global legal framework that allows them to request, collect, and release global animal or human health information: the World Organisation for Animal Health (OIE), which is responsible for transparently assessing the global animal health situation, and the World Health Organization (WHO), which is responsible for transparently assessing the global human health situation. Legal instruments bind OIE Member Countries and WHO States Parties (OIE's Standards and WHO's International Health Regulations [IHR]) to report certain disease outbreaks and public health events to their respective organisations. OIE Member Countries must report exceptional epidemiological events involving any OIE-listed diseases, including zoonoses. Moreover, they must notify the OIE of any emerging animal diseases. The IHR require WHO Member States to provide notification of events that may constitute a public health emergency of international concern. These include, but are not restricted to, outbreaks of communicable diseases of international concern. In both organisations, in addition to reporting outbreaks and exceptional events, Members also monitor diseases on an ongoing basis and provide regular reports. To complement these passive surveillance mechanisms, the OIE, WHO and the Food and Agriculture Organization of the United Nations track signals from informal sources of outbreaks of animal and zoonotic infectious diseases, thereby increasing the sensitivity of worldwide disease reporting. The formal information collected is disseminated to Members and the general public through various communication channels, so that countries can apply science-based measures to prevent further disease spread. Both the OIE and WHO reporting systems are supported by a range of coordinating activities to ensure the proper flow of information between national and international levels.
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http://dx.doi.org/10.20506/rst.36.2.2672 | DOI Listing |
Porcine Health Manag
January 2025
Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, Campus de la Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Spain.
Background: Digestive disorders are one of the main health problems in suckling piglets. The correct visual identification of feces in suckling piglets is an important tool for the diagnosis of enteric diseases. The aim of the present observational study was to analyze different physicochemical parameters of the feces of suckling piglets aged 0 to 21 days: visual appearance (color and consistency), fecal dry matter (FDM) content and pH.
View Article and Find Full Text PDFSkelet Muscle
January 2025
Department of Molecular Physiology and Biophysics, and Department of Neurology, Howard Hughes Medical Institute, Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Background: Maintaining the connection between skeletal muscle fibers and the surrounding basement membrane is essential for muscle function. Dystroglycan (DG) serves as a basement membrane extracellular matrix (ECM) receptor in many cells, and is also expressed in the outward-facing membrane, or sarcolemma, of skeletal muscle fibers. DG is a transmembrane protein comprised of two subunits: alpha-DG (α-DG), which resides in the peripheral membrane, and beta-DG (β-DG), which spans the membrane to intracellular regions.
View Article and Find Full Text PDFPorcine Health Manag
January 2025
Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Grønnegårdsvej 2, Frederiksberg C, 1870, Denmark.
Background: Umbilical outpouchings (UOs) in pigs are a multifactorial disease and little is known about effective prevention strategies and risk factors for UO development. UOs are common in Danish pigs and legislation complicates and increases the cost of keeping and raising pigs with UO. Recommendations for preventive measures exist but the scientific evidence behind the recommendations is often lacking.
View Article and Find Full Text PDFAnim Microbiome
January 2025
Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL, 32610, USA.
Background: Cows that develop metritis experience dysbiosis of their uterine microbiome, where opportunistic pathogens overtake uterine commensals. An effective immune response is critical for maintaining uterine health. Nonetheless, periparturient cows experience immune dysregulation, which seems to be intensified by prepartum over-condition.
View Article and Find Full Text PDFArthritis Res Ther
January 2025
Scientific Research Center, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130033, China.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation, tissue damage, and fibrosis, significantly affecting the quality of life. While there are currently some effective treatments available, they often come with side effects. There is an urgent need to find new treatments that can further improve therapeutic outcomes and reduce side effects.
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