Tracheoesophageal fistulas (TEF) are pathologic communications between the esophagus and the trachea or bronchi. The development of a TEF can result from malignant or benign etiologies. A common approach for the treatment of TEFs is the placement of endobronchial and esophageal stents to facilitate healing of the communication. This case report describes the successful treatment of a TEF resulting from calcified mediastinal lymphadenopathy due to a previous Histoplasmosis capsulatum infection. In addition to placement of endobronchial and esophageal stents, the non-healing TEF was treated with ACell (Gentrix) decellularized porcine urinary bladder matrix to facilitate complete closure of the fistulous tract.
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http://dx.doi.org/10.1093/jscr/rjy187 | DOI Listing |
Cureus
December 2024
Nephrology, Hospital Clinic Barcelona, Barcelona, ESP.
Histoplasmosis, caused by the fungus , is a significant public health concern in endemic regions like Mexico. Immunocompromised individuals, especially those with HIV infection and those exposed to nitrogen-rich environments, such as bird excrement or bat guano, are particularly vulnerable. This case report describes a middle-aged patient with jaundice in the skin and mucous membranes.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
St Pauls Eye Clinic, Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.
We report a rare case of a rapidly growing and large conjunctival histoplasmosis lesion in an immunosuppressed West African woman in her 80s, affecting her only eye. The patient had undergone a renal transplant and was on immunosuppressive medications. Additionally, she had previously been treated for presumed systemic histoplasmosis with itraconazole more than 5 years ago.
View Article and Find Full Text PDFCureus
November 2024
Department of Dermatology, University of Nebraska Medical Center, Omaha, USA.
is a dimorphic fungus that causes pulmonary, disseminated, or, rarely, primary cutaneous disease. Primary cutaneous histoplasmosis presents with non-specific skin lesions, which can lead to poor patient outcomes due to diagnostic challenges and delays in diagnosis. A 62-year-old male on immunosuppressive medications for lupus nephritis presented to the emergency department with 24 hours of altered mental status.
View Article and Find Full Text PDFCureus
November 2024
General Medicine, Hospital General Atlántida, La Ceiba, HND.
Cureus
September 2024
Pulmonology and Critical Care, Freeman Hospital West, Joplin, USA.
Histoplasmosis, caused by , often mimics the appearance of lung cancer on fludeoxyglucose (FDG) positron emission tomography (PET) scans. The "flip-flop fungus," due to its similar presentation on imaging modalities, can lead to false-positive results and unnecessary invasive testing. We present a 46-year-old male patient with a lung nodule and bilateral hilar lymphadenopathy on an FDG-PET scan who initially presented with chest discomfort.
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