AI Article Synopsis

  • Tomato Dicer-like2 (slDCL2) helps plants fight off viruses like potato virus X and tobacco mosaic virus.
  • It makes small RNA molecules that help protect the plants and are important for their defense.
  • Scientists found that using special RNA can boost these protective molecules, making plants even better at resisting these viruses.

Article Abstract

Tomato Dicer-like2 (slDCL2) is a key component of resistance pathways against potato virus X (PVX) and tobacco mosaic virus (TMV). It is also required for production of endogenous small RNAs, including miR6026 and other noncanonical microRNAs (miRNAs). The 2 mRNAs are targets of these slDCL2-dependent RNAs in a feedback loop that was disrupted by target mimic RNAs of miR6026. In lines expressing these RNAs, there was correspondingly enhanced resistance against PVX and TMV. These findings illustrate a novel miRNA pathway in plants and a crop protection strategy in which miRNA target mimicry elevates expression of defense-related mRNAs.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120711PMC
http://dx.doi.org/10.1101/gad.313601.118DOI Listing

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