In patients with autoimmune disease, gynecomastia should not be considered as 1 of the first signs of hyperthyroidism, rather it is a breast pathology that can be present even when euthyroidism restoration is achieved. It is unknown whether the autoimmune nature of thyroid disorders or simply the hyperthyroidism effects breast changes.
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| http://dx.doi.org/10.1002/ccr3.1565 | DOI Listing |
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Thyroid and cardiovascular diseases.
Turk J Med Sci
December 2024
Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Ankara University, Ankara, Turkiye.
The thyroid gland is one of the major regulator organs of hemostasis in the human body, controlling the functioning of numerous systems. Thyroid hormones exert a modulating effect on the cardiovascular system in particular, ensuring optimal functioning within the normal range. Triiodothyronine (T3), as an active form of thyroid hormone, is mainly responsible for this effect via both genomic and nongenomic mechanisms.
View Article and Find Full Text PDFHyperthyroid cats that develop azotemia following successful radioiodine treatment have shorter survival times compared to cats that remain nonazotemic.
J Am Vet Med Assoc
December 2024
2College of Veterinary Medicine, Cornell University, Ithaca, NY.
Objective: Many hyperthyroid cats (15% to 50%) have concurrent chronic kidney disease (CKD) that is "masked" and will not become azotemic until after treatment. Previous studies reported that mild-to-moderate azotemic CKD after methimazole or thyroidectomy does not adversely affect survival. Our objective was to determine whether hyperthyroid cats with masked CKD rendered euthyroid with radioiodine (131I) have shorter survival than 131I-treated euthyroid cats that remain nonazotemic.
View Article and Find Full Text PDFEffects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.
Front Endocrinol (Lausanne)
December 2024
Department of Endocrinology and Metabolism, The Institute of Endocrinology, National Health Commision of the People's Repiublic of China (NHC) Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China.
Clinicians often consider the use of dietary supplements to assist in lowering thyroid autoantibody titres in patients with Hashimoto's thyroiditis (HT). Currently, different supplements differ in their ability to reduce autoantibody levels. The purpose of this article is to compare the ability of different supplements to lower autoantibody titres and restore TSH levels through a systematic literature review.
View Article and Find Full Text PDFRole of Supplementation with Selenium and Myo-Inositol Versus Selenium Alone in Patients of Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis.
Clin Med Insights Endocrinol Diabetes
December 2024
Dow University of Health Sciences, Karachi, Pakistan.
Objective: The main objective was to assess the therapeutic efficacy of selenium alone versus a combination of myo-inositol and selenium (MI + Se) in treating patients with autoimmune thyroiditis (AIT). The study aims to determine which treatment option is more effective in restoring euthyroid state, as indicated by changes in thyroid-stimulating hormone (TSH), T3, T4, thyroid peroxidase antibodies (TPOAb), and thyroglobulin antibodies (TgAb).
Methods: Google Scholar and PubMed databases were searched for randomized controlled trials (RCTs) and observational studies that reported outcomes of combined treatment (MI + Se) in restoring a euthyroid state, specifically comparing it with selenium-only (Se-only) treatment.
Assessment of thiol-disulfide and glutathione homeostasis after levothyroxine replacement in individuals with autoimmune or nonautoimmune hypothyroidism.
Arch Endocrinol Metab
October 2024
Ankara City Hospital Ankara Türkiye Ankara City Hospital, Medical Biochemistry, Ankara, Türkiye.
Article Synopsis
- The study aimed to explore the relationship between hypothyroidism and oxidative stress markers in women, specifically assessing conditions like Hashimoto's thyroiditis and nonautoimmune hypothyroidism after treatment with levothyroxine.
- A total of 116 women participated, with findings showing that both hypothyroid groups exhibited lower levels of important antioxidant compounds compared to healthy controls, indicating a shift towards oxidative stress.
- Despite treatment with levothyroxine, the hypothyroid groups did not show significant improvement in oxidative stress marker levels, suggesting that the treatment may not effectively address the oxidative stress associated with these conditions.
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