Immunization of Solid Organ Transplant Candidates and Recipients: A 2018 Update.

Infect Dis Clin North Am

Division of Infectious Diseases & Immunology, University of Massachusetts Medical School, 55 Lake Avenue North, S7-715, Worcester, MA 01655, USA. Electronic address:

Published: September 2018

This article discusses the recommended vaccines used before and after solid organ transplant period, including data regarding vaccine safety and efficacy and travel-related vaccines. Vaccination is an important part of the preparation for solid organ transplantation, because vaccine-preventable diseases contribute to the morbidity and mortality of these patients. A pretransplantation protocol should be encouraged in every transplant center. The main goal of vaccination is to provide seroprotection before transplantation, because iatrogenically immunosuppressed patients posttransplant have a lower seroresponse to vaccines.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.idc.2018.04.002DOI Listing

Publication Analysis

Top Keywords

solid organ
12
organ transplant
8
immunization solid
4
transplant candidates
4
candidates recipients
4
recipients 2018 update
4
2018 update article
4
article discusses
4
discusses recommended
4
recommended vaccines
4

Similar Publications

Background: This study aims to analyze the patient characteristics, clinical outcomes, and contemporary trends concerning type A aortic dissection (TAAD) in previous recipients of abdominal solid organ transplantation (ASOT) in the United States.

Methods: The National Inpatient Sample was queried to identify all patients aged ≥18 with TAAD and a history of ASOT (TAAD-ASOT) between 2002 and 2015Q3 using ICD-9 diagnosis and procedure codes. Baseline characteristics and in-hospital outcomes were compared between TAAD-ASOT patients and TAAD patients without a history of ASOT (TAAD-non-ASOT).

View Article and Find Full Text PDF

Reduction of Central Line-Associated Bloodstream Infections on a Transplant Unit.

J Nurs Care Qual

March 2025

Author Affiliations: Director Patient Care-Oncology, Surgery, & Transplant Services, Emory University Hospital, Atlanta, GA (Ms Spinks); Solid Organ Transplant, Unit Nurse Educator, Emory University Hospital, Atlanta, GA (Ms Berhanu); Solid Organ Transplant, Education Coordinator, Emory University Hospital, Atlanta, GA (Mr Buenvenida); Solid Organ Transplant, Unit Director, Emory University Hospital, Atlanta, GA (Ms Henry); Division of Transplantation, Emory University School of Medicine, Atlanta, GA (Dr Lo); and Infection Preventionist, Infection Prevention and Control Department, Emory University Hospital, Atlanta, GA (Dr Yun).

Background: Central line-associated bloodstream infection (CLABSI) is a preventable complication of central venous catheters (CVC) that can result in prolonged hospitalization, increased cost, and mortality.

Local Problem: CLABSI rates in a solid organ transplant unit were above the National Database of Nursing Quality Indicators target.

Methods: Evidence-based CLABSI prevention interventions were implemented using the Plan-Do-Study-Act process.

View Article and Find Full Text PDF

A rhizobacterium-secreted protein induces lateral root development through the IAA34-PUCHI pathway.

Cell Rep

March 2025

Key Lab of Organic-based Fertilizers of China and Jiangsu Provincial Key Lab for Solid Organic Waste Utilization, Nanjing Agricultural University, Nanjing 210095, China. Electronic address:

Lateral roots (LRs) can continuously forage water and nutrients from soil. In Arabidopsis thaliana, LR development depends on a canonical auxin signaling pathway involving the core transcription factors INDOLE-3-ACETIC ACIDs (IAAs) and AUXIN RESPONSE FACTORs (ARFs). In this study, we identified a protein, bacillolysin, secreted by the beneficial rhizobacterium Bacillus velezensis SQR9, that is able to stimulate LR formation of Arabidopsis.

View Article and Find Full Text PDF

Minimal Residual Disease in Metastatic Soft Tissue Sarcoma.

Curr Treat Options Oncol

March 2025

Division of Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

Liquid biopsies represent a promising and minimally invasive approach to diagnosing and monitoring cancer. In recent years, studies across a multitude of solid organ malignancies have suggested the clinical utility of biomarkers such as circulating tumor DNA (ctDNA). Particular attention has been given to serial assessment of such biomarkers in an effort to detect minimal residual disease (MRD), in order to predict which patients may be at highest risk of relapse following curative-intent surgical or medical intervention.

View Article and Find Full Text PDF

Cordycepin, a natural adenosine derivative, exhibits multiple pharmacological effects on organisms. However, its distribution and metabolic characteristics have not been fully elucidated in vivo. In this study, ultra-high liquid chromatography tandem high-resolution mass spectrometry (UHPLC-HRMS/MS) was used to investigate the pharmacokinetic characteristics and effects of cordycepin on endogenous adenosine and inosine.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!