Pathological variants of hepatocellular carcinoma on MRI: emphasis on histopathologic correlation.

Abdom Radiol (NY)

Department of Diagnostic Radiology, Tan Tock Seng Hospital, 11, Jalan Tan Tock Seng, Singapore, 308433, Singapore.

Published: February 2019

AI Article Synopsis

  • Hepatocellular carcinoma (HCC) can be diagnosed primarily using imaging techniques, with MRI being the most effective due to its sensitivity and specificity.
  • MRI allows for better evaluation of complex liver lesions and provides detailed information on cellularity and fat content.
  • The review aims to illustrate the various types of HCC on MRI, highlighting how their different biological and histological characteristics can affect their imaging appearance.

Article Abstract

Hepatocellular carcinoma (HCC) is a unique tumor because it is one of the few cancers which can be treated based on imaging alone. Magnetic resonance imaging (MRI) carries higher sensitivity and specificity for the diagnosis of HCC than either computed tomography (CT) or ultrasound. MRI is imaging modality of choice for the evaluation of complex liver lesions and HCC because of its inherent ability to depict cellularity, fat, and hepatocyte composition with high soft tissue contrast. The imaging features of progressed HCC are well described. However, many HCC tumors do not demonstrate classical imaging features, posing a diagnostic dilemma to radiologists. Some of these can be attributed to variations in tumor biology and histology, which result in radiological features that differ from the typical progressed HCC. This pictorial review seeks to demonstrate the appearance of different variants of HCC on MRI imaging, in relation to their histopathologic features.

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Source
http://dx.doi.org/10.1007/s00261-018-1749-zDOI Listing

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