AI Article Synopsis
- Enterocytozoon bieneusi is a widespread pathogen in sheep and goats that poses risks to livestock development and public health, but limited research exists on native breeds in China.
- In a study in Yunnan province, 70 out of 661 fecal specimens (about 10.59%) tested positive for the pathogen in both black-boned sheep and goats, with no significant prevalence difference between the two species.
- Twelve genotypes of E. bieneusi were identified, including ten known variants and two new ones, with phylogenetic analysis showing some of these genotypes are zoonotic, indicating potential transmission to humans and the need for better infection management strategies among local livestock.
Article Abstract
Enterocytozoon bieneusi is a common pathogen in sheep and goats worldwide, threatening husbandry development and public health. However, there were few reports on native breeds of sheep and goats in China. In the present study, we investigated the prevalence and multi-locus genotypes (MLGs) of E. bieneusi in two important local breeds, black-boned sheep and goats, in Yunnan province, southwestern China. Of 661 faecal specimens collected from five counties of Yunnan province, 70 (10.59%) were positive for E. bieneusi infection. Infections were found in both black-boned sheep and goats, but no significant difference in prevalence was detected between two species. E. bieneusi was found in all age groups of black-boned sheep, while no infections were observed in 0-2-month black-boned goats. 12 genotypes were identified based on sequence variations of the internal transcribed spacer, including 10 known genotypes (BEB6, COS I, SX1, CM21, CHG3, CHG1, CHS5, EbpC, COS II, PigEb4) and two novel genotypes (named as YNS1 and YSM1), with BEB6 as the prevalent genotype both in black-boned sheep and goats. Phylogenetic analysis indicated that three genotypes of them, namely EbpC, CHS5 and PigEb4, were clustered into the zoonotic group 1, while the remaining nine genotypes were belonged to the host-adapted group 2. Multi-locus sequence typing (MLST) revealed 12 distinct multilocus genotypes (MLGs), with 11 MLGs detected in black-boned sheep and only one found in one black-boned goat. These findings expanded the reservoirs of E. bieneusi and provided fundamental data for controlling E. bieneusi infection in native small ruminants as well as other hosts in this province.
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| http://dx.doi.org/10.1016/j.meegid.2018.08.022 | DOI Listing |
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