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Safety and feasibility of balloon aortic valvuloplasty in non-TAVI centers: The "BAV for life" experience. | LitMetric

AI Article Synopsis

  • - The study aimed to assess the safety and effectiveness of balloon aortic valvuloplasty (BAV) performed by trained operators in hospitals that do not conduct transcatheter aortic valve implantation (TAVI).
  • - A total of 55 high-risk patients with severe aortic valve stenosis underwent BAV; the results showed significant improvements in aortic valve function without major complications, and survival rates were similar to those treated at TAVI centers.
  • - The research concluded that BAV is a viable option for patients at high risk for more invasive procedures, reinforcing its safety and efficacy in non-TAVI clinical settings.

Article Abstract

Objectives: To evaluate the safety and the feasibility of balloon aortic valvuloplasty (BAV) procedure made by trained operators in centers not performing transcatheter aortic valve implantation (TAVI).

Background: BAV is a valuable therapeutic tool for patients with symptomatic severe aortic valve stenosis (AS) at prohibitive risk for TAVI or surgery.

Methods: Consecutive high-risk AS patients underwent BAV in five non-TAVI centers, where BAV operators had completed a 6-month training period in high-volume TAVI centers (Group A). All clinical, echocardiographic, and procedural data were prospectively collected and compared with data of patients treated in TAVI center (Group B).

Results: Between June 2016 and June 2017, 55 patients (83.9 ± 7.0 years) were enrolled: 25 in Group A and 30 in Group B. After BAV, a substantial reduction of the peak-to-peak aortic valve gradient was obtained in both groups (-35.3 ± 15.2 vs -28.8 ± 13.9 mmHg, P =0.25). No major bleeding or vascular complications occurred. In-hospital death was observed in three patients of Group A and two patients of Group B (P =0.493). The mean follow-up time was 303 ± 188 days; no patients were lost. The 1-year survival free from overall death (Group A 75.8% vs Group B 68.8%; P =0.682) and heart failure rehospitalization (Group A 73.0% vs Group B 66.8%; P =0.687) was similar in the two groups. At multivariable analysis, low left ventricular (LV) ejection fraction (HR: 0.943; P = 0.011) and cardiogenic shock (HR: 5.128; P = 0.002) at admission were independent predictors of mortality.

Conclusions: BAV is a safe and effective procedure that can be performed by trained operators in centers not performing TAVI.

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Source
http://dx.doi.org/10.1002/ccd.27820DOI Listing

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