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Structural and Functional Remodeling for Elite Cyclists During Exercise; Pressure Volume Loops and Hemodynamic Forces Analysis.
Am J Physiol Heart Circ Physiol
January 2025
Sport Medicine Unit, Careggi University Hospital, Via delle Oblate 4, 50134 Florence, Italy.
The study was designed to investigate the pattern of intraventricular Hemo-Dynamic Forces (HDF) and myocardial performance during exercise in Elite Cyclists (EC). Transthoracic stress echocardiography was performed on nineteen EC and thirteen age-matched sedentary controls (SC) at three incremental exercise intensities based on Heart Rate Reserve (HRR). Left Ventricular (LV) HDF were computed from echocardiography long-axis data sets using a novel technique based on endocardial boundary tracking, both in apex-base and latero-septal directions.
View Article and Find Full Text PDFQuantification of Albumin and ɣ-Globulin Concentrations by Multivariate Regression Based on Admittance Relaxation Time Distribution (mrARTD).
Biomed Phys Eng Express
January 2025
Dept. Mechanical Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, Chiba, 263-8522, JAPAN.
Albumin and γ-globulin concentrations in subcutaneous adipose tissues (SAT) have been quantified by multivariate regression based on admittance relaxation time distribution (mraRTD) under the fluctuated background of sodium electrolyte concentration. The mraRTD formulates P = Ac + Ξ (P: peak matrix of distribution function magnitude ɣP and frequency τP, c: concentration matrix of albumin cAlb, γ-globulin Gloc, and sodium electrolyte Nac, A: coefficient matrix of a multivariate regression model, and Ξ: error matrix). The mraRTD is implemented by two processes which are: 1) the training process of A through the maximum likelihood estimation of P and 2) the quantification process of cAlb, Gloc, and Nac through the model prediction.
View Article and Find Full Text PDFHypothesis for Molecular Evolution in the Pre-Cellular Stage of the Origin of Life.
Wiley Interdiscip Rev RNA
January 2025
Institute for Ocean Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen, People's Republic of China.
Life was originated from inorganic world and had experienced a long period of evolution in about 3.8 billion years. The time for emergence of the pioneer creations on Earth is debatable nowadays, and how the scenario for the prebiotic molecular interactions is still mysterious.
View Article and Find Full Text PDFPsychological and Behavioral Insights From Social Media Users: Natural Language Processing-Based Quantitative Study on Mental Well-Being.
JMIR Form Res
January 2025
Smith School of Business, Queen's University, Kingston, ON, Canada.
Background: Depression significantly impacts an individual's thoughts, emotions, behaviors, and moods; this prevalent mental health condition affects millions globally. Traditional approaches to detecting and treating depression rely on questionnaires and personal interviews, which can be time consuming and potentially inefficient. As social media has permanently shifted the pattern of our daily communications, social media postings can offer new perspectives in understanding mental illness in individuals because they provide an unbiased exploration of their language use and behavioral patterns.
View Article and Find Full Text PDFDevelopment of an eHealth Intervention Including Self-Management for Reducing Sedentary Time in the Transition to Retirement: Participatory Design Study.
JMIR Form Res
January 2025
Division of Psychology, School of Health, Care and Social Welfare, Mälardalen University, Västerås/Eskilstuna, Sweden.
Background: Having a great amount of sedentary time is common among older adults and increases with age. There is a strong need for tools to reduce sedentary time and promote adherence to reduced sedentary time, for which eHealth interventions have the potential to be useful. Interventions for reducing sedentary time in older adults have been found to be more effective when elements of self-management are included.
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