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Challenges in Toxocariasis Diagnosis: From Pericarditis, through Hepatic Tumor, to the Detection of Brain Aneurysms: Case Report.
Pathogens
March 2024
Department of Infectious Diseases, Liver Diseases and Acquired Immune Deficiences, Wroclaw Medical University, 51-149 Wroclaw, Poland.
Article Synopsis
- The condition can lead to visceral and ocular larva migrans, with rare cases involving the central nervous system (neurotoxocariasis), potentially causing serious issues like meningitis or seizures.
- There is concern about the underdiagnosis of neurotoxocariasis due to its vague symptoms, and while a link to aneurysms hasn't been proven, it's suggested as an area for future research.
Background incidence rates of health outcomes in populations at risk for Lyme disease using US administrative claims data.
Vaccine
February 2024
IQVIA, Falls Church, VA, USA.
Background: Background incidence rates (IRs) of health outcomes in Lyme disease endemic regions are useful to contextualize events reported during Lyme disease vaccine clinical trials or post-marketing. The objective of this study was to estimate and compare IRs of health outcomes in Lyme disease endemic versus non-endemic regions in the US during pre-COVID and COVID era timeframes.
Methods: IQVIA PharMetrics® Plus commercial claims database was used to estimate IRs of 64 outcomes relevant to vaccine safety monitoring in the US during January 1, 2017-December 31, 2019 and January 1, 2020-December 31, 2021.
Clinical and epidemiological features of Lyme neuroborreliosis in adults and factors associated with polyradiculitis, facial palsy and encephalitis or myelitis.
Sci Rep
November 2023
Clinic of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Article Synopsis
- The study focused on analyzing Lyme neuroborreliosis (LNB) in hospitalized adults in eastern Lithuania from 2010 to 2021, including 103 patients (100 with early LNB, 3 with late LNB).
- Early LNB frequently presented as polyradiculitis (75% of patients), with peripheral facial palsy occurring in 53% of cases, while 14% developed encephalitis or myelitis.
- A significant portion (73.8%) of patients left the hospital with lingering symptoms, and predictors for various syndromes included factors like the absence of erythema migrans (EM) and the presence of fever or pleocytosis.
[CME: Neuroborreliosis].
Praxis (Bern 1994)
October 2022
Innere Medizin, Kantonsspital Graubünden, Schweiz.
Article Synopsis
- Lyme disease is the most common tick-borne infection in Europe, caused by bacteria from the Borrelia complex, and initially appears as a skin infection known as Erythema migrans.
- If untreated, it can lead to serious complications like neurological Lyme disease, Lyme carditis, and Lyme arthritis, with neuroborreliosis affecting 3-15% of patients, potentially causing polyradiculitis or meningitis.
- Treatment for neuroborreliosis typically involves antibiotics such as doxycycline, ceftriaxone, or penicillin G, while prevention focuses on reducing tick exposure, and a vaccine is being developed in Europe.
Covid-19 vaccines and neurological complications: a systematic review.
Z Naturforsch C J Biosci
January 2023
Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
The COVID-19 mainly causes respiratory disorders with high infection and severe morbidity and mortality. Neurologists have concerns about potential neurological side effects, profits, and timing of COVID-19 vaccines. This study aimed to review systematically research for the COVID-19 vaccine and neurological complications.
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