Background: Falls are a common cause of hospitalization, morbidity, and mortality among the elderly in the United States. Evidence-based imaging recommendations for evaluation of delayed intracranial hemorrhage (DICH) are not generally agreed upon. The purpose of this project was to evaluate the incidence of DICH detected by head computer tomography (CT) among an elderly population on pre-injury anticoagulant or antiplatelet (ACAP) therapy.
Methods: Data from a Level 1 Trauma Center trauma registry was used to assess the incidence of DICH in an elderly population of patients (≥65 years) who sustained a minor fall while on pre-injury ACAP medications. Counts and percentages are reported.
Results: Data on 1076 elderly trauma patients were downloaded, of which 838 sustained a minor fall and 513 were found to be using a pre-injury ACAP medication. One patient (0.46%) with a DICH was identified out of 218 patients who received a routine repeat head CT. Aspirin and warfarin were the most common pre-injury ACAP medications and 19.27% (42/218) of patients were found to be using multiple ACAP medications.
Conclusions: Universal screening protocols promote immediate-term patient safety, but do so at a great expense with respect to health expenditures and increased radiation exposure. This analysis highlights the need for an effective risk assessment tool for DICH that would reduce the burden of unnecessary screenings while still identifying life-threatening intracranial hemorrhages in affected patients.
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http://dx.doi.org/10.1186/s12873-018-0179-0 | DOI Listing |
Cureus
November 2024
Trauma and Acute Care Surgery, Desert Regional Medical Center, Palm Springs, USA.
Falls from escalators, although infrequent, can result in a wide array of injuries, ranging from minor lacerations to fatal outcomes. This retrospective study aims to detail the treatment and outcomes of eight patients who sustained blunt-force trauma from escalator falls and received care at Desert Regional Medical Center in Palm Springs, California. Among these eight patients, seven required hospitalization, with three necessitating intensive care unit (ICU) admission, and two patients ultimately succumbing to their injuries.
View Article and Find Full Text PDFArch Phys Med Rehabil
December 2024
Gillette Children's - James R. Gage Center for Gait and Motion Analysis, Saint Paul, Minnesota, USA; University of Minnesota - Twin Cities, Department of Orthopedic Surgery, Minneapolis, Minnesota, USA. Electronic address:
Objective: To quantify physical and psychosocial impacts of falls by age and Gross Motor Classification System (GMFCS) level in ambulatory individuals with cerebral palsy (CP).
Design: Cross-Sectional Survey.
Setting: Tertiary specialty hospital and online CP communities.
Neural Netw
December 2024
School of Computer Science and Technology, Xi'an Jiaotong University, Xi'an, China. Electronic address:
Transferable adversarial examples, which are generated by transfer-based attacks, have strong adaptability for attacking a completely unfamiliar victim model without knowing its architecture, parameters and outputs. While current transfer-based attacks easily defeat surrogate model with minor perturbations, they struggle to transfer these perturbations to unfamiliar victim models. To characterize these untransferable adversarial examples, which consist of natural examples and perturbations, we define the concept of fuzzy domain.
View Article and Find Full Text PDFInquiry
December 2024
Appleton Institute, Central Queensland University, Wayville, SA, Australia.
This study explored measures of subjective and objective sleep health and the association with fall occurrence and falls risk for older adults. A longitudinal observational study was conducted with participants in residential aged care (n = 36) and community dwelling (n = 35) settings. At baseline, objective sleep data involved wearing wrist worn accelerometers and measuring falls risk by walking using the Quantitative timed up and go (QTUG) of a simple, cognitive, and motor task.
View Article and Find Full Text PDFMolecules
December 2024
TB Alliance, 80 Pine St. 20th Floor, New York, NY 10005, USA.
AE90015 is a highly specific and effective negative allosteric modulator (NAM) for the human mGlu5 receptor, showing significant promise for treating Parkinson's disease. An in vivo rat oral dose study was conducted on AE90015, which involved the collection of urine and bile samples over a 24 h period. At the study's endpoint, plasma, liver, brain, and renal tissues were also collected.
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