AI Article Synopsis
Article Abstract
[This corrects the article DOI: 10.1371/journal.pgen.1007296.].
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108455 | PMC |
| http://dx.doi.org/10.1371/journal.pgen.1007565 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mendelian randomization analysis of the brain, cerebrospinal fluid, and plasma proteome identifies potential drug targets for attention deficit hyperactivity disorder.
EBioMedicine
July 2024
Affiliated Mental Health Center & Hangzhou Seventh People's Hospital and School of Brain Science and Brain Medicine, Zhejiang University School of Medicine, Hangzhou, 310058, China; Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, 1369 West Wenyi Road, Hangzhou, 311121, China; NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou, 310058, China. Electronic address:
Article Synopsis
- Researchers are looking for new treatments for ADHD by studying proteins in the brain, fluid around the brain, and blood to find what's causing it.
- They used special methods to analyze many samples and see if proteins might be linked to ADHD and other related conditions.
- They found seven proteins that are connected to ADHD risk, with GMPPB showing a strong link across different types of ADHD and also affecting related disorders.
Integrating plasma proteomes with genome-wide association data for causal protein identification in multiple myeloma.
BMC Med
September 2023
Department of Hematology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Background: Multiple myeloma (MM) is a severely debilitating and fatal B-cell neoplastic disease. The discovery of disease-associated proteins with causal genetic evidence offers a chance to uncover novel therapeutic targets.
Methods: First, we comprehensively investigated the causal association between 2994 proteins and MM through two-sample mendelian randomization (MR) analysis using summary-level data from public genome-wide association studies of plasma proteome (N = 3301 healthy individuals) and MM (598 cases and 180,756 controls).
Genomic and genetic sequence information of strains assigned to the genus reveal the great heterogeneity of the group and identify strain DSM 123 as the authentic type strain of this species.
Int J Syst Evol Microbiol
June 2020
College of Science and Technology, Bellevue University, Bellevue, Nebraska 68005, USA.
The genus , containing purple nonsulfur photosynthetic Proteobacteria, has a number of strains that belong to different species, although many of them are collectively called . The type species and closely related species are the focus of this paper. The comparison of available genome sequences indicate that the following species are well recognized: (strains ATH 2.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!