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http://dx.doi.org/10.1212/CPJ.0000000000000481 | DOI Listing |
J Community Hosp Intern Med Perspect
November 2024
Department of Internal Medicine, HCA Healthcare, MountainView Hospital, 2880 N Tenaya Way, 89128, Las Vegas, NV, USA.
Paraneoplastic limbic encephalitis (PLE) is a poorly understood condition, thought to be caused by the cross-reacting of tumor antibodies with neurons in the brain, resulting in neuropsychiatric sequelae, such as personality and behavioral changes, psychosis, memory loss, and seizures. Anti-contactin-associated protein-like 2 (CASPR2) antibodies can cause PLE in patients with particular tumors, which in most cases can be identified as thymoma, lung cancer, or endometrial cancer. Some case reports show rare instances with other tumors, such as throat or sigmoid carcinoma.
View Article and Find Full Text PDFPediatr Int
January 2025
Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Japan.
Neurol Sci
December 2024
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, 510000, China.
We aimed to define the clinical features and outcomes of encephalitis associated with anti-GAD65 Abs. In addition, we reviewed cases published in the literature with GAD65 encephalitis. We retrospectively studied 482 consecutive patients attending a tertiary care center for evaluation of an autoimmune neurological disorder.
View Article and Find Full Text PDFCureus
November 2024
Neurology, Park Hospital, Gurgaon, IND.
We report a primigravida 31-year-old female patient hospitalized at 32 gestational weeks with status epilepticus. In due course of illness, she developed refractory status epilepticus managed with induced coma with propofol and emergency early lower section caesarean surgery (LSCS). A battery of initial laboratory and radiological tests did not lead to a definite diagnosis.
View Article and Find Full Text PDFCureus
December 2024
Neurology, UT Health San Antonio, San Antonio, USA.
Autoimmune encephalitis is a disorder characterized by an autoantibody-mediated process that leads to brain inflammation. It is associated with neurological symptoms including cognitive issues, psychiatric problems, seizures, and autonomic dysfunctions. Anti-leucine-rich glioma-inactivated 1 limbic encephalitis (anti-LGI1 LE) is a rare type of autoimmune LE with a unique presentation, comprising neuropsychiatric disturbances, sleep disorders, and faciobrachial dystonic seizures (FBDS).
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