Background: A substantial growth has been reported in Iran's number of clinical, biomedical, and public health research publications over the last 30 years. It is of interest to investigate whether this quantitative growth has also led to a larger number of papers with a high citation impact; to explore where the capacity for performing research lies; and which fields/institutions are lagging behind.
Methods: This was a bibliometric study. Web of Science Core Collection and its different tools were used for retrieving and analysing the publications. Information about the journals was found on Journal Citation Reports. Different types of collaborations across the highly-cited papers was investigated based on the affiliations, the characteristics of the language of the authors' names, and the authors' study and work backgrounds.
Results: Iran's number of clinical, biomedical, and public health research publications has substantially increased since 2000, a surge was seen in 2007, and the figure reached a peak in 2011. 11% of the publications were in Pharmacology Pharmacy; and the majority originated in Tehran University of Medical Sciences. Six of the 10 journals that had published the most were Iranian journals. H-index of publications had also increased over time (almost doubled between 2000 and 2010). 30.9% of the most-cited publications had only relied on Iranian resources (including 48 publications); had been published in journals with impact factors ranging between 0.4 and 8.3; and the majority were original basic sciences research.
Conclusions: In Iran, a great capacity for research lies in clinical, biomedical, and public health fields which can be strengthened with further investment. It is important to use this capacity in a way that would align with the national population health needs. It is also essential to consider the limitations of only relying on bibliometric tools for assessing health research activities. Finally, the Iranian science policy-makers are encouraged to (i) support the researchers and institutions that have proved research capacity; (ii) direct further resources towards research areas and/or institutions that are lagging behind; (iii) facilitate further international collaboration with the academics and/or institutions that have shown the capacity for conducting successful research projects with Iran.
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http://dx.doi.org/10.7189/jogh.08.020701 | DOI Listing |
Gut Microbes
December 2025
Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), West China Second University Hospital, Sichuan University, Chengdu, China.
Necrotizing Enterocolitis (NEC) is a severe, life-threatening inflammatory condition of the gastrointestinal tract, especially affecting preterm infants. This review consolidates evidence from various biomedical disciplines to elucidate the complex pathogenesis of NEC, integrating insights from clinical, microbial, and molecular perspectives. It emphasizes the modulation of NEC-associated inflammatory pathways by probiotics and novel biologics, highlighting their therapeutic potential.
View Article and Find Full Text PDFDrugs
January 2025
Lysosomal Storage Disorders Unit, Royal Free London NHS Foundation Trust, University College London, London, NW3 2QG, UK.
Lysosomal storage disorders (LSDs) are rare inherited metabolic disorders characterized by defects in the function of specific enzymes responsible for breaking down substrates within cellular organelles (lysosomes) essential for the processing of macromolecules. Undigested substrate accumulates within lysosomes, leading to cellular dysfunction, tissue damage, and clinical manifestations. Clinical features vary depending on the degree and type of enzyme deficiency, the type and extent of substrate accumulated, and the tissues affected.
View Article and Find Full Text PDFClin Rheumatol
January 2025
Department of Public Health, University of Murcia, Campus de Ciencias de la Salud, Murcia, 30120, Spain.
Introduction: Therapeutic drug monitoring (TDM) in inflammatory rheumatic diseases (RMDs) is gaining interest. However, there are unresolved questions about the best practices for implementing TDM effectively in clinical settings.
Objective: The primary objective of this study was to evaluate whether early TDM of adalimumab predicts drug survival at 52 weeks in patients with RMDs.
J Community Genet
January 2025
Graduate Program in Structural and Functional Biology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
In 2018, Portuguese researchers proposed the "Tool for Quality Assessment of Genetic Counseling," a 5-point Likert scale comprising 50 items across five dimensions, designed to assess genetic counseling from the professional's perspective. This descriptive, cross-sectional study aimed to adapt this tool to Brazilian Portuguese, validate it among Brazilian clinical geneticists, and conduct a preliminary assessment of the quality of genetic counseling in Brazil. The adaptation process involved expert-driven content validation and calculation of the Content Validity Index (CVI) to ensure equivalence between the original and adapted versions.
View Article and Find Full Text PDFJ Endocrinol Invest
January 2025
Division of Internal Medicine 4 and Hypertension Unit, Department of Medical Sciences, University of Torino, Torino, Italy.
Purpose: The delayed or missed diagnosis of secondary hypertension contributes to the poor blood pressure control worldwide. This study aimed to assess the diagnostic approach to primary aldosteronism (PA) and pheochromocytoma (PHEO) among Italian centers associated to European and Italian Societies of Hypertension.
Methods: Between July and December 2023, a 10-items questionnaire was administered to experts from 82 centers of 14 Italian regions and to cardiologists from the ARCA (Associazioni Regionali Cardiologi Ambulatoriali) Piemonte.
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