[This corrects the article DOI: 10.1371/journal.pone.0201459.].
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203103 | PLOS |
Foods
November 2024
College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Ochratoxin A (OTA) is a naturally occurring mycotoxin mainly produced by certain species of and and is a serious threat to human health and food safety. Previous studies showed that ML17 can completely degrade 1 μg/mL of OTA. The aim of this study was to investigate the degradation effect of ML17 at different concentrations of OTA, and specifically, to investigate the mechanism of OTA degradation by ML17.
View Article and Find Full Text PDFFront Immunol
December 2024
Fourth Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, Fujian, China.
Invasive aspergillosis (IA) significantly increases mortality in critically ill patients in the ICU and its occurrence is closely related to immunocompromise. Dissemination of IA is easily misdiagnosed and mistreated due to its ability to invade multiple systems throughout the body and lack of typical clinical manifestations. In this case, a 25-year-old previously healthy woman was hospitalized with fulminant myocarditis and treated with veno-arterial extracorporeal membrane pulmonary oxygenation (VA-ECMO) support and intravenous acyclovir, high-dose methylprednisolone, and immunoglobulin.
View Article and Find Full Text PDFMicrobiol Res
February 2025
Institute of Microbial Genetics, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna (BOKU), Tulln a.d. Donau 3430, Austria; Research Platform Bioactive Microbial Metabolites (BiMM), Konrad Lorenz Strasse 24, Tulln a.d. Donau 3430, Austria. Electronic address:
Organisms are repeatedly exposed to fluctuating environmental and nutritional conditions. Transcriptional memory has been shown to be a mechanism to cope with these fluctuations because it increases the speed and the magnitude of the cellular response to a certain re-occurring condition and therefore optimizes adaptation and fitness in a given environment. We found that genes coding for sterigmatocystin (ST) production in Aspergillus nidulans are activated stronger when cells are repeatedly exposed to nutrient starvation, compared to cells that experience this condition for the first time.
View Article and Find Full Text PDFBone Marrow Transplant
November 2024
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Chronic granulomatous disease (CGD) is a disorder of immunity characterized by phagocyte dysfunction. Mold infections in patients with CGD are often severe and disseminated. We present patient characteristics, microbiological data, and outcomes for 26 patients with CGD who received hematopoietic cell transplantation (HCT) or gene therapy-modified cells (GT) between 2008 and 2019, with proven fungal infection either before or during their transplant.
View Article and Find Full Text PDFJ Environ Sci Health B
November 2024
Centro de Biotecnología Genómica del Instituto Politécnico Nacional, Reynosa, Tamaulipas, México.
In northern Tamaulipas, México, the contamination of corn by toxigenic fungi reduces grain production and quality. Corn contaminated by mycotoxins puts humans and livestock at risk. Continuous monitoring of the sanitary quality of grain at harvest and in storage will define preventive and corrective strategies for contamination by mycotoxigenic fungi.
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