The experiment was aimed at studying the structural reorganization of the knee joint synovium in dogs with modeling of primary osteoarthrosis (MOP) and tibial lengthening (TL). The methods of light microscopy and histomorphometry of semithin epoxy sections were used to assess the thickness of synovial surface layer, number of synoviocyte layers, characterize the cells, to measure the numerical density of vessels, and to define the changes of the nerves and cell composition of the subsynovial layer. In MOP-group, the predominance of type А synoviocytes, hypovascularity and irreversible changes in the nerves of subsynovial sheath were observed. In TL-group, the diversity of type В synoviocyte forms and sizes, hypervascularity of subsynovial layer and signs of its re-innervation were detected. It is concluded that the hyperplastic synoviopathy is possible in cases of both hypo- and hypervascularization of subsinovial layer.

Download full-text PDF

Source

Publication Analysis

Top Keywords

knee joint
8
changes nerves
8
subsynovial layer
8
histological changes
4
changes knee
4
joint synovial
4
synovial fluid
4
fluid experimental
4
experimental modeling
4
modeling osteoarthrosis
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!