The article Two-year outcome after recurrent implantation failure: prognostic factors and additional interventions.
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http://dx.doi.org/10.1007/s00404-018-4873-7 | DOI Listing |
Front Oncol
January 2025
Department of Pediatrics, Children's Healthcare of Atlanta, Atlanta, GA, United States.
Background: Pediatric low-grade gliomas (pLGGs) have an overall survival of over 90%; however, patients harboring a BRAF alteration may have worse outcomes, particularly when treated with classic chemotherapy. Combined BRAF/MEK inhibition following incomplete resection demonstrated improved outcome in BRAF altered pLGG compared to combined carboplatin/vincristine chemotherapy and is now considered the standard FDA-approved treatment for this group of tumors. The aim herein was to investigate the efficacy and tolerability of single agent BRAF inhibitor treatment in BRAF altered pLGG.
View Article and Find Full Text PDFCureus
December 2024
Department of Orthopaedic Surgery, The Jikei University School of Medicine, Tokyo, JPN.
Osteoporotic vertebral fractures (OVFs) in elderly patients pose challenges due to bone destruction and surgical risks. This case report describes a minimally invasive approach using calcium phosphate cement (CPC) vertebroplasty and short fusion with cement augmentation of pedicle screws (CAPS) in a 91-year-old woman with severe OVF. The patient underwent CPC vertebroplasty at L1 and CAPS fixation at T12-L2, followed by osteoporosis medication.
View Article and Find Full Text PDFFront Pediatr
January 2025
Division of Metabolic Diseases and Hepatology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
Acid sphingomyelinase deficiency (ASMD) is a rare, progressive lysosomal storage disorder resulting from a deficiency in acid sphingomyelinase, leading to sphingomyelin accumulation and multi-organ damage. ASMD presents a broad phenotypic spectrum with a continuum of severity, making it challenging to predict the phenotype in very young children and differentiate between acute and chronic neurovisceral disease. No disease-specific treatments existed for ASMD.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
Department of Obstetrics, Division Women and Baby, Birth Centre Wilhelmina's Children Hospital, University Medical Centre Utrecht, Utrecht University, UMC Utrecht, 3508 AB, Utrecht, Postbus 85090, the Netherlands.
Background: Optimizing CS performance is a global health priority, given the maternal and perinatal morbidity and mortality associated with both underuse and overuse. This study aims to (1) determine the facility-based CS rate in Suriname and explore which women are most likely to undergo a CS and (2) classify all CS by the WHO Robson classification and analyze the perinatal outcomes.
Methods: An observational, cross-sectional study in Suriname, using nationwide birth registry data that included all hospital births in 2020 and 2021 (≥ 27 weeks of gestation).
NPJ Biodivers
January 2025
Laboratory of Apiculture & Social Insects, Department of Ecology & Evolution, School of Life Sciences, University of Sussex, Brighton, UK.
This is a critical moment for land use policy globally, with many countries (e.g. the UK and the European Union) currently undertaking significant green reforms of their agricultural policies.
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