Peripheral synovial sarcoma rarely metastasizes to the head and neck. A case report of such an occurrence involving the ear is presented, along with a review of the subject. The case report is unique, as it is the only reported instance of synovial sarcoma involving the ear.
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Eur J Cancer
January 2025
Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Background: Epidemiological data for sarcoma in adolescents and young adults (AYAs) and across age groups are limited. We aim to: 1) update sarcoma incidence, survival, and changes over time in European AYAs; 2) provide an updated comparison of sarcoma survival in AYAs versus children and mature adults.
Methods: We calculated crude incidence rates (IR) per 100,000 European population per year from 2006 to 2013.
BMJ Case Rep
January 2025
Department of Orthopaedic Surgery, Pontificia Universidad Catolica de Chile, Santiago, RM, Chile
The hindfoot is an uncommon site for malignant tumours. While limb salvage procedures are now more common for treating bone sarcoma, there is limited information available on hindfoot reconstruction alternatives because of its low incidence and its challenging outcomes. We present a case report of a man in his late 60s with synovial sarcoma affecting the right heel (calcaneus and soft tissue).
View Article and Find Full Text PDFJBJS Case Connect
January 2025
Department of Surgery, Plastic and Reconstructive Surgical Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Case: Wide resection of a synovial sarcoma of the anteromedial distal leg involving the dimetaphyseal tibia and posterior tibial tendon produced an 8.5-cm osseous defect. To keep the free flap from invaginating into the defect and prevent kinking of the anastomosis, six 1.
View Article and Find Full Text PDFAnticancer Agents Med Chem
January 2025
Department of Oncology, the First Affiliated Hospital of Zhengzhou University, Henan Zhengzhou, 450052, China.
Background: Anlotinib has demonstrated durable clinical benefits in patients with unresectable or metastatic bone and soft-tissue sarcomas.
Methods: 92 patients treated with chemotherapy combined with or without anlotinib were collected and analyzed. The objective response rate (ORR) and disease control rate (DCR) were analyzed.
Radiol Case Rep
March 2025
Department of Radiology, Columbia University College of Physicians and Surgeons, Harlem Hospital Center, New York, NY, USA.
Synovial sarcoma is a common but aggressive subset of sarcomatous tumors that often arises adjacent to the large joints of extremities. We present a case of a 33-year-old male with no medical history and an initial complaint of right leg pain. On further radiological and pathological investigation, he was diagnosed with synovial sarcoma in the medial soft tissues of his thigh.
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