Bisalbuminemia is an uncommon finding that is seen as bifid albumin peak on serum protein electrophoresis. We report here this unusual finding in an adult male diagnosed with multiple myeloma on routine workup.
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http://dx.doi.org/10.1007/s12288-017-0911-z | DOI Listing |
Metabol Open
September 2024
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527, Athens, Greece.
Bisalbuminemia is a rare, typically benign condition marked by the presence of a bifid albumin band on serum protein electrophoresis. It can either be inherited due to a point mutation or acquired in association with various medical conditions, most commonly diabetes mellitus. Bisalbuminuria, the presence of bifid albumin in urine, may or may not accompany bisalbuminemia.
View Article and Find Full Text PDFEJIFCC
December 2023
Consultant, department of Biochemistry, Basavatarakam Indo-American Cancer Hospital and Research Institute, Hyderabad, India.
Bisalbuminemia is a rare, benign, protein anomaly presenting with two distinct peaks of albumin on serum protein electrophoresis. It reflects the presence of a normal albumin and a modified albumin in the same individual. This condition can be either hereditary or acquired.
View Article and Find Full Text PDFClin Chim Acta
January 2024
Department of Pathology, University of Texas Medical Branch, Galveston, TX, United States. Electronic address:
Int J Mol Sci
January 2022
Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.
The human albumin gene, the most abundant serum protein, is located in the long arm of chromosome 4, near the centromere, position 4q11-3. It is divided by 14 intervening introns into 15 exons, the last of which is untranslated. To date, 74 nucleotide substitutions (mainly missense) have been reported, determining the circulating variants of albumin or pre-albumin.
View Article and Find Full Text PDFJ Lab Physicians
September 2021
Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
The incidence of a bifid electrophoretic pattern in the albumin region on serum protein electrophoresis is an infrequent phenomenon. The availability of literature from India is scarce and is limited to case reports. The aim of the study is to analyze the frequency of bisalbuminemia in an Indian referral facility.
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