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| http://dx.doi.org/10.1503/cmaj.180973 | DOI Listing |
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Long-range directional growth of neurites induced by magnetic forces.
Acta Biomater
January 2025
School of Life Sciences, Keele University, Staffordshire, UK. Electronic address:
The ability to control the growth and orientation of neurites over long distances has significant implications for regenerative therapies and the development of physiologically relevant brain tissue models. In this study, the forces generated on magnetic nanoparticles internalised within intracellular endosomes are used to direct the orientation of neuronal outgrowth in cell cultures. Following differentiation, neurite orientation was observed after 3 days application of magnetic forces to human neuroblastoma (SH-SY5Y) cells, and after 4 days application to rat cortical primary neurons.
View Article and Find Full Text PDFLiquid Polycaprolactone (PCL) for Reversing PXE's Skin Laxity of Inner Thighs and Knees: A Case Report.
J Cosmet Dermatol
December 2024
Department of Biology and Nanomedicine, National and Kapodistrian University of Athens, Athens, Greece.
Background/aim: Pseudoxanthoma elasticum (PXE) is a genetic connective tissue disorder that affects the skin with limited treatment options. A recent technology employing particle-free polycaprolactone (PCL) has shown promising results in treating inner thighs and kness of a 27-year-old female patient. This article provides a case report along with our detailed treatment protocol based on the efficacy of PCL in reversing skin laxity that can be easily incorporated into the therapeutic approaches for patients with PXE.
View Article and Find Full Text PDFExperimental Measurement-Device-Independent Quantum Conference Key Agreement.
Phys Rev Lett
November 2024
Shenzhen Institute for Quantum Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China.
Article Synopsis
- - Quantum networks facilitate secure communication by enabling tasks like Quantum Conference Key Agreement (QCKA), which allows multiple users to share secure keys.
- - Traditional QCKA struggles with long-distance key distribution due to the delicate nature of Greenberger-Horne-Zeilinger (GHZ) states, but Measurement-Device-Independent QCKA (MDI-QCKA) offers a solution by improving security and reducing loopholes.
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Nature's Secret Neuro-Regeneration Pathway in Axolotls, Polychaetes and Planarians for Human Therapeutic Target Pathways.
Int J Mol Sci
November 2024
Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, Kuala Nerus 21030, Terengganu, Malaysia.
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- Restoring nerve injury in humans is challenging, especially in the central nervous system (CNS), where factors like glial scars hinder regeneration compared to the peripheral nervous system (PNS), which relies on Schwann cells for support.
- Unlike humans, some species like axolotls and planarians can regenerate their nervous systems thanks to abundant pluripotent stem cells that can differentiate into various cell types.
- Understanding the molecular pathways of these regenerating species may provide insights and new strategies for improving nerve regeneration therapies in humans.
Metals in Wildfire Suppressants.
Environ Sci Technol Lett
November 2024
Department of Civil and Environmental Engineering, University of Southern California, Los Angeles, California 90089, United States.
Article Synopsis
- Frequent and severe wildfires in the American West have led to increased use of fire suppression products, including long-term fire retardants and Class A foams, which have unknown formulations due to trade secrets.
- Concerns have arisen regarding increased metal concentrations in soils and waters post-fire, with this study examining whether fire suppression products contribute to this issue.
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