Functional outcomes after glossectomies: Pilot study on use of a thrombin-fibrinogen biosponge (TachoSil).

Oral Surg Oral Med Oral Pathol Oral Radiol

Department of Oral and Maxillofacial Surgery, Bellvitge University Hospital, L´ Hospitalet de Llobregat, Barcelona, Spain.

Published: January 2019

Objective: The aim of this study was to investigate whether the use of a thrombin-fibrinogen biosponge (TachoSil) has any advantage in tongue healing.

Study Design: A retrospective study with 30 patients treated with partial glossectomy (below half a tongue) was designed. We compared the results from a group using the biosponge (n =15 patients) and a control group (n = 15). Variables taken into consideration were bolus clearance, frenulum flexibility, and oral transit time. With these parameters, we formulated a "tongue remaining functional" (TRF) scale to assess tongue functionality after the surgery. We also evaluated long-term quality of life by using the Functional Intraoral Glasgow Scale (FIGS).

Results: In this study, TRF score, bolus clearance, oral transit time, and frenulum flexibility were significantly improved in the biosponge group. However, there were no differences between the 2 groups in the FIGS scores.

Conclusions: The use of the biosponge in this pilot study showed positive long-term effects in lingual healing and functionality after partial glossectomies.

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Source
http://dx.doi.org/10.1016/j.oooo.2018.07.007DOI Listing

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