The aim of the present study was to evaluate different biological activities of fungus (Family Hypocreaceae). isolated for the first time from the cucumber soil (rhizosphere). It was tested as antimicrobial, antioxidant and anticancer agent. from the cucumber soil (rhizosphere) caused inhibition of the mycelial growth of and . Also, the alcoholic extract of the fungal mycelia proved a potent antibacterial activity against coli and . In addition, it exhibited a significant antifungal activity against and at 100 µg/disc. Study of the antimicrobial and antioxidant activities of the volatile constituents had been done. The antioxidant, anticancer and antiviral activities of the isolated proteins, and carbohydrates were determined. Furthermore, the volatile constituents were isolated from fresh mycelia of and subjected to GC/MS analysis. Total protein (10%), carbohydrate (19.57%), steroidal (13.95%) and triterpenoidal content (38.34%) were determined in the alcoholic extract of mycelia. In conclusion, this fungus showed antioxidant, anticancer, antiviral and antibacterial effects. Further studies must be done to identify the molecules responsible for its effect and to consider its application in the pharmacological and medicinal purposes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059106 | PMC |
| http://dx.doi.org/10.1080/21501203.2017.1423126 | DOI Listing |
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