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Article Abstract
Background: HLA-B38:02 has been shown to be associated with antithyroid drug-induced agranulocytosis in Asian patients.
Methods: HLA-B38:02 was analyzed by sequence-based typing in 21 patients who developed antithyroid drug-induced agranulocytosis and in 81 controls.
Results: Frequency of HLA-B38:02 was 52.4% in agranulocytosis patients compared to 3.7% in controls (OR = 28.6, 95% CI = 6.8-120.2).
Conclusions: HLA-B38:02 is a significant risk factor for agranulocytosis in Kinh Vietnamese patients treated with antithyroid drug.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079452 | PMC |
| http://dx.doi.org/10.1155/2018/7965346 | DOI Listing |
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