[Development of New Digital Phantom Creation Tool for Evaluation of Low-contrast Detectability Using Iterative Reconstruction].

Purpose: We developed a novel digital phantom-creation tool that will help formulate the standard shooting method for a three-phase dynamic liver study. Here, we present data demonstrating the usefulness of this tool in the assessment of low-contrast detectability and visibility.

Methods: We performed a visual evaluation by adding a spherical digital phantom with a diameter of 8 mm and a computed tomography (CT) value difference of 10 Hounsfield unit (HU) to images taken using filtered back projection and seven types of adaptive iterative dose reduction 3D (Weak, Mild, eMild, Standard, eStandard, Strong, and eStrong). We also examined the partial-volume effect by drawing a profile curve using a digital phantom with a CT value difference of 30 HU and a diameter of 5 mm. Furthermore, a digital phantom with two kinds of filters (smoothing and Gaussian) was added to the image of the home-made simulated tumor phantom to visual valuate its visibility in the phantom's low-contrast module and the digital phantom.

Results: Detection sensitivity was significantly decreased in Standard, eStandard, Strong, and eStrong, and the area under the curve also decreased in a similar fashion. We confirmed that the partial-volume effect was due to the different maximum CT values in the profile curve at 4 and 5 mm thickness. The visibility of the low-contrast module and digital phantom was most consistent when using the Gaussian filter.

Conclusion: This tool can be used for low-contrast detection ability evaluation.